Marine sponge alkaloids as a source of anti-bacterial adjuvants.
Marine sponge alkaloids as a source of anti-bacterial adjuvants.
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海洋海绵生物碱是抗菌佐剂的来源。
DOI:
10.1016/j.bmcl.2016.11.018
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发表时间:
2016-12-15
影响因子:
2.7
通讯作者:
Melander C
中科院分区:
文献类型:
--
作者:
Melander RJ;Liu HB;Stephens MD;Bewley CA;Melander C
Novel approaches that do not rely upon developing microbicidal compounds are sorely needed to combat multidrug resistant (MDR) bacteria. The potential of marine secondary metabolites to serve as a source of non-traditional anti-bacterial agents is demonstrated by showing that pyrrole-imidazole alkaloids inhibit biofilm formation and suppress antibiotic resistance.
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