Carvacrol promotes intestinal health in Pengze crucian carp, enhancing resistance to Aeromonas hydrophila
Carvacrol promotes intestinal health in Pengze crucian carp, enhancing resistance to Aeromonas hydrophila
复制标题
香芹酚促进彭泽鲫鱼肠道健康，增强对嗜水气单胞菌的抵抗力
DOI：
10.1016/j.aqrep.2020.100325
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发表时间：
2020-07
影响因子：
3.7
通讯作者：
Siming Li
中科院分区：
文献类型：
--
作者：
Wenshu Liu;Xiaoze Guo;Yanliang Chen;Yanqiang Tang;Haihong Xiao;Siming Li
本试验旨在研究微胶囊香芹酚对肉鸡生长、抗A.研究了彭泽鲫肠道细菌、肠道形态和肠道细胞因子等肠道健康指标。彭泽）。鱼被分成四组。每组饲喂不同的饮食56天（对照饮食或添加200、400或600 mg/kg MC的饮食）。我们的结果表明，MC对生长没有影响，但显着降低A。在400和600 mg/kg剂量下观察到与感染相关的死亡率，600 mg/kg剂量下的死亡率最低。将接受对照饮食的鱼的肠道健康与接受600 mg/kg MC的组的肠道健康进行比较。高通量测序结果表明，MC增加了梭菌门的丰度。增加了鲸类细菌的丰度，减少了黄杆菌和假单胞菌的丰度。光学显微镜和透射电子显微镜图像支持MC的能力，以提高固有层的完整性，增加微绒毛的高度，并加强紧密连接，特别是在前肠。ELISA分析表明，肠道促炎细胞因子的水平，包括肿瘤坏死因子-α和白细胞介素-1 β，降低，而抗炎细胞因子白细胞介素-10的水平增加的鱼管理的饮食MC。结论香芹酚可改善肠道菌群组成、改善肠道形态结构、减轻肠道炎症反应，从而增强机体对A.养殖彭泽鲫鱼。
This study was performed to determine the effects of dietary microencapsulated carvacrol (MC) on growth, resistance toA. hydrophila, and intestinal health parameters including intestinal bacteria, intestinal morphology and intestinal cytokines, in Pengze crucian carp (Carassius auratusvar. Pengze). Fish were divided into four groups. Each group was fed a different diet for 56 days (a control diet or diets supplemented with 200, 400, or 600 mg/kg of MC). Our results indicate that MC had no effect on growth but significantly decreasedA. hydrophilainfection-associated mortality rates at 400 and 600 mg/kg and the lowest mortality was present at 600 mg/kg. The intestinal health of fish receiving the control diet was compared with that of the group receiving 600 mg/kg MC. High-throughput sequencing showed that MC increased the abundance of phylum Fusobacteria. It also increased the abundance of the genusCetobacteriumand decreased those ofFlavobacteriumandPseudomonas. Light microscopy and transmission electron microscopy images support the ability of MC to improve the integrity of the lamina propria, increase microvilli height, and strengthen tight junctions, especially in the foregut. An ELISA assay indicated that levels of intestinal pro-inflammatory cytokines, including tumor necrosis factor-α and interleukins-1β, were reduced, whereas the level of the anti-inflammatory cytokine interleukins-10 was increased of fish administered dietary MC. We conclude that carvacrol promotes intestinal bacteria composition, intestinal morphology status and reduces intestinal inflammatory, which enhances resistance toA. hydrophilain Pengze crucian carp.
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影响因子：
3.6
作者：
E. Ringø;E. Ringø;Irene Salinas;Irene Salinas;R. Olsen;A. Nyhaug;Reidar Myklebust;Terry M Mayhew-Terr
通讯作者：
E. Ringø;E. Ringø;Irene Salinas;Irene Salinas;R. Olsen;A. Nyhaug;Reidar Myklebust;Terry M Mayhew-Terr
DOI：
10.1093/bioinformatics/btx692
发表时间：
2018-03-01
期刊：
Bioinformatics (Oxford, England)
影响因子：
--
作者：
Polanski K;Gao B;Mason SA;Brown P;Ott S;Denby KJ;Wild DL
通讯作者：
Wild DL
DOI：
10.5713/ajas.2011.11006
发表时间：
2011-06
期刊：
Asian-australasian Journal of Animal Sciences
影响因子：
--
作者：
J. D. Kim;T. Nhut;T. N. Hải;C. Ra
通讯作者：
J. D. Kim;T. Nhut;T. N. Hải;C. Ra
影响因子：
7
作者：
Zeng Z;Zhang S;Wang H;Piao X
通讯作者：
Piao X
影响因子：
14.9
作者：
Pruesse E;Quast C;Knittel K;Fuchs BM;Ludwig W;Peplies J;Glöckner FO
通讯作者：
Glöckner FO