Tobacco use among adults initiating treatment for HIV infection in rural Uganda.

Tobacco use among adults initiating treatment for HIV infection in rural Uganda.
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DOI:
10.1007/s10461-014-0737-8
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发表时间:
2014-07
期刊:
影响因子:
4.4
通讯作者:
Rigotti, Nancy A.
Rigotti, Nancy A.
中科院分区:
医学2区
文献类型:
--
作者:
Kruse, Gina R.;Bangsberg, David R.;Hahn, Judith A.;Haberer, Jessica E.;Hunt, Peter W.;Muzoora, Conrad;Bennett, John P.;Martin, Jeffrey N.;Rigotti, Nancy A.

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我们对乌干达姆巴拉拉开始抗逆转录病毒治疗(ART)的成人烟草使用情况进行了纵向研究,根据2011年人口与健康调查,该地区有11%的男性和3%的女性使用烟草。在一个前瞻性队列中,在开始ART之前评估了自我报告的烟草使用情况,并每3-4个月重新评估一次。血浆可替宁,尼古丁代谢产物,在成人ART前的一个子集中进行测量,以验证自我报告。在496例受试者中,50例(10%)报告了当前的烟草使用情况(20%的男性,6%的女性)。大多数(53%)可替宁水平升高(>15 ng/mL)的成年人报告没有吸烟。在ART开始后6个月,33%的烟草使用者戒烟(95% CI=20-46%)。到5年时,64%的人戒烟(95% CI=47-77%)。开始抗逆转录病毒疗法的乌干达农村人自我报告的烟草使用率是当地背景人口的两倍,并且使用率可能被低估。ART启动可能是戒烟干预的一个机会。
We conducted a longitudinal study of tobacco use among adults initiating antiretroviral therapy (ART) in Mbarara, Uganda where 11% of men and 3% of women use tobacco according to the 2011 Demographic and Health Survey. In a prospective cohort, self-reported tobacco use was assessed before starting ART and reassessed every 3–4 months. Plasma cotinine, a nicotine metabolite, was measured in a subset of adults pre-ART to verify self-report. Among 496 subjects, 50 (10%) reported current tobacco use (20% of men, 6% of women). Most (53%) adults with elevated cotinine levels (>15 ng/mL) reported no tobacco use. By 6 months after ART initiation, 33% of tobacco users had quit (95% CI=20–46%). By 5 years, 64% quit (95% CI=47–77%). Self-reported tobacco use among rural Ugandans starting ART was twice as common as among the local background population and use may be underreported. ART initiation could be an opportunity for tobacco cessation interventions.
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发表时间: 2009-06
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