Theranostic nanoplatforms for simultaneous cancer imaging and therapy: current approaches and future perspectives.
Theranostic nanoplatforms for simultaneous cancer imaging and therapy: current approaches and future perspectives.
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DOI：
10.1039/c1nr11277e
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发表时间：
2012-01-21
期刊：
影响因子：
6.7
通讯作者：
Chen X
中科院分区：
文献类型：
--
作者：
Choi KY;Liu G;Lee S;Chen X
体视学是指影像与治疗相结合的概念。作为一个不断发展的新领域，它与传统的影像和治疗学既有联系又有区别。它包含了多种技术，以获得全面的诊断、活体分子图像和个性化的治疗方案。最近，有一种趋势是将这些努力与新兴材料和纳米技术相结合，试图开发新的平台和方法来解决临床上的实际问题。在这篇文章中，将讨论合理设计的纳米粒子同时用于癌症成像和治疗的主题。几个典型的纳米颗粒平台，如聚合物纳米颗粒、金纳米材料、碳纳米管、磁性纳米颗粒和二氧化硅纳米颗粒将被详细阐述，并将讨论基于纳米颗粒系统的未来挑战。
Theranostics is a concept which refers to the integration of imaging and therapy. As an evolving new field, it is related to but different from traditional imaging and therapeutics. It embraces multiple techniques to arrive at a comprehensive diagnostic, in vivo molecular images and an individualized treatment regimen. More recently, there is a trend of tangling these efforts with emerging materials and nanotechnologies, in an attempt to develop novel platforms and methodologies to tackle practical issues in clinics. In this article, topics of rationally designed nanoparticles for the simultaneous imaging and therapy of cancer will be discussed. Several exemplary nanoparticle platforms such as polymeric nanoparticles, gold nanomaterials, carbon nanotubes, magnetic nanoparticles and silica nanoparticles will be elaborated on and future challenges of nanoparticle-based systems will be discussed.
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影响因子：
15
作者：
Cheng, Kai;Peng, Sheng;Xu, Chenjie;Sun, Shouheng
通讯作者：
Sun, Shouheng
影响因子：
11.2
作者：
Choi, Yongdoo;Weissleder, Ralph;Tung, Ching-Hsuan
通讯作者：
Tung, Ching-Hsuan
影响因子：
4.6
作者：
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通讯作者：
Kotov, Nicholas A.
DOI：
10.1073/pnas.0601755103
发表时间：
2006-04-18
影响因子：
11.1
作者：
Farokhzad, OC;Cheng, JJ;Langer, R
通讯作者：
Langer, R
影响因子：
10.8
作者：
Gobin, Andre M.;Lee, Min Ho;West, Jennifer L.
通讯作者：
West, Jennifer L.