Race/ethnic differences in bone mineral densities in older men.
Race/ethnic differences in bone mineral densities in older men.
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DOI：
10.1007/s00198-010-1188-3
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发表时间：
2010-12
影响因子：
4
通讯作者：
Cauley, J. A.
中科院分区：
文献类型：
--
作者：
Nam, H. -S.;Shin, M. -H.;Zmuda, J. M.;Leung, P. C.;Barrett-Connor, E.;Orwoll, E. S.;Cauley, J. A.
比较不同人种/种族组的BMD。即使在非洲或亚洲血统中，BMD也存在显著的种族/民族差异。对体型的额外调整大大削弱或逆转了美国白人男性与亚洲男性之间的差异。它说明了身体大小对这些群体之间差异的作用。关于不同种族/民族和地理位置的男性骨矿物质密度（BMD）水平的流行病学信息不足。在一项横断面设计中，我们比较了四个国家七个种族/民族老年男性的BMD。测量男性股骨颈、全髋和腰椎BMD男性骨质疏松性骨折（MrOS）研究的受试者（年龄65 - 78岁）（美国4，074例白人、208例非裔美国人、157例亚洲人和116例西班牙裔男性），托巴哥骨健康研究MrOS香港研究（1，747名香港中国男性）和Namwon研究（1，079名韩国男性）。根据所有扫描仪的跨部位校准结果校正BMD。与美国白人男性相比，非洲裔加勒比人和非洲裔美国人男性在所有三个骨部位的年龄校正平均BMD分别高出8-20%和6-11%。美国白人和西班牙裔男性的髋关节BMD相似，美国亚洲人、中国香港人和韩国男性除股骨颈外，所有骨部位的BMD均低3-14%。对体重和身高的额外调整大大减弱或逆转了美国白人男性与亚洲男性（包括美国亚洲人、中国香港人和韩国男性）之间的差异。在亚洲人群中，韩国男性股骨颈BMD较高，全髋BMD较低。这些发现表明，即使在非洲或亚洲血统内，BMD也存在显著的种族/民族差异，并说明了体型对亚洲男性与其他男性之间差异的重要作用。
BMD was compared across race/ethnic groups. There were substantial race/ethnic differences in BMD even within African or Asian origin. Additional adjustment for body size greatly attenuated or reversed the differences between US Caucasian men vs Asian men. It illustrates the role of body size on the difference between these groups. There is insufficient epidemiologic information about men’s bone mineral density (BMD) levels across race/ethnic groups and geographic locations. In a cross-sectional design, we compared BMD in older men across seven race/ethnic groups in four countries. Femoral neck, total hip, and lumbar spine BMD were measured in men (age 65 to 78 years) from the Osteoporotic Fractures in Men (MrOS) Study (4,074 Caucasian, 208 African-American, 157 Asian, and 116 Hispanic men in USA), Tobago Bone Health Study (422 Afro-Caribbean men), MrOS Hong Kong Study (1,747 Hong Kong Chinese men), and the Namwon Study (1,079 South Korean men). BMD was corrected according to the cross-site calibration results for all scanners. When compared with US Caucasian men, Afro-Caribbean and African-American men had, respectively, 8–20% and 6–11% higher age-adjusted mean BMD at all three bone sites. Hip BMD was similar in US Caucasian and Hispanic men, US Asian, Hong Kong Chinese, and Korean men had 3–14% lower BMD at all bone sites except femoral neck in Korean men. Additional adjustment for weight and height greatly attenuated or reversed the differences between US Caucasian men vs Asian men including US Asian, Hong Kong Chinese, and South Korean men. Among Asian groups, Korean men had higher femoral neck BMD and lower total hip BMD. These findings show substantial race/ethnic differences in BMD even within African or Asian origin and illustrate the important role of body size on the difference between Asian men and others.
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影响因子：
4
作者：
Lau, EMC;Leung, PC;Cauley, J
通讯作者：
Cauley, J
影响因子：
6.2
作者：
Hui, SL;Gao, SJ;Genant, H
通讯作者：
Genant, H
影响因子：
5
作者：
BLOCK, G;HARTMAN, AM;GARDNER, L
通讯作者：
GARDNER, L
影响因子：
168.9
作者：
Center, JR;Nguyen, TV;Eisman, JA
通讯作者：
Eisman, JA
影响因子：
4
作者：
Hill, D. D.;Cauley, J. A.;Zmuda, J. M.
通讯作者：
Zmuda, J. M.