Biological Evaluation of Garcinia kola Heckel.
Biological Evaluation of Garcinia kola Heckel.
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DOI：
10.1155/2022/3837965
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发表时间：
2022
影响因子：
2.8
通讯作者：
Lema, Abubakar Abdullahi
中科院分区：
文献类型：
--
作者：
Dogara, Abdulrahman Mahmoud;Hamad, Saber W.;Hama, Harmand A.;Bradosty, Sarwan W.;Kayfi, Soran;Al-Rawi, Sawsan S.;Lema, Abubakar Abdullahi
藤黄属（Garcinia kola）是藤黄科（Clusiaceae）、Malpighiales目（Malpighiales）的藤黄属（Garcinia）植物。它在地球仪上有180多个成员。它遍布亚洲和热带非洲国家。在非洲，传统上，G kola用于管理和治疗癌症，糖尿病，疟疾，止痛药，高血压和其他许多疾病。本文旨在全面更新有关藤黄果的药理潜力的相关信息。ScienceDirect、PubMed、Wiley、Google Scholar、Hindawi和Springer等电子数据库从原始科学研究论文中提取了有价值的信息。入选标准。抗氧化剂、抗微生物剂、抗糖尿病剂、抗菌剂、药物、抗病毒剂、传统药物、民族药理学、毒性、细胞毒性作用、化学成分、矿物元素、GCMS分析和任何其他相关短语用作筛选器以查找研究。排除标准。来自可疑在线来源的数据，以及论文报告和评论出版物，被排除在本次调查之外。研究表明，G.可乐果作为抗氧化剂、抗微生物剂、抗糖尿病剂、抗高血压剂、抗镇痛剂和抗炎剂非常有效。该研究还发现，过多食用种子会导致生育力低下和毒性。但G.科拉还没有在人类中进行全面评估，需要进一步精心设计的临床试验来证实临床前的发现。应检查种子提取物的作用机制。应建立种子的标准剂量和安全性。
Garcinia kola belongs to the Garcinia genus of the Clusiaceae family and Malpighiales order. It contains more than 180 members all over the globe. It is found all over Asia and in tropical African countries. In Africa, traditionally, G kola is used to manage and treat cancer, diabetes, malaria, analgesics, hypertension, and other numerous ailments. This review aimed to comprehensively update relevant information regarding the pharmacological potential of Garcinia kola. Electronic databases such as ScienceDirect, PubMed, Wiley, Google Scholar, Hindawi, and Springer extracted valuable information from original scientific research papers. Inclusion Criteria. Antioxidant, antimicrobial, antidiabetic, antibacterial, medications, antiviral, traditional medicine, ethnopharmacology, toxicity, cytotoxic action, chemical composition, mineral elements, GCMS analysis, and any other related phrases were used as filters to find studies. Exclusion Criteria. Data from questionable online sources, as well as thesis reports and review publications, were excluded from this investigation. The investigation revealed that seeds of G. kola are very efficient as antioxidant, antimicrobial, antidiabetic, antihypertension, antianalgesic, and anti-inflammatory. The study also found that too much consumption of the seeds caused low fertility and toxicity. However, the safety and efficacy of G. kola have not been wholly assessed in humans, and further well-designed clinical trials are needed to corroborate preclinical findings. The mechanism of action of the seed extract should be examined. The standard dose and safety of the seed should be established.
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影响因子：
0.4
作者：
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通讯作者：
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影响因子：
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作者：
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作者：
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DOI：
10.4236/abb.2021.1211025
发表时间：
2021-01-01
期刊：
Advances in Bioscience and Biotechnology
影响因子：
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作者：
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通讯作者：
Monsi, Tombari Pius
影响因子：
0.9
作者：
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通讯作者：
Abdulrahman, Mahmoud Dogara