Cognitive function after bariatric surgery: evidence for improvement 3 years after surgery.

Cognitive function after bariatric surgery: evidence for improvement 3 years after surgery.
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DOI:
10.1016/j.amjsurg.2013.05.018
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发表时间:
2014-06
影响因子:
3
通讯作者:
Gunstad, John
Gunstad, John
中科院分区:
医学3区
文献类型:
--
作者:
Alosco, Michael L.;Galioto, Rachel;Spitznagel, Mary Beth;Strain, Gladys;Devlin, Michael;Cohen, Ronald;Crosby, Ross D.;Mitchell, James E.;Gunstad, John

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减肥手术与认知改善有关,并且这种改善可能在长期随访中发现。我们假设减肥手术后3年认知改善仍能维持。从减肥手术的纵向评估父项目中招募了50名减肥患者。参与者在术后12周、12个月、24个月和36个月完成了计算机化认知测试组合,以评估认知功能。重复测量显示的主要影响的注意力,执行功能和记忆。注意力在24个月内有所改善,然后略有下降,但仍在36个月的平均范围内。执行功能的改善在术后36个月达到顶峰。记忆力的短期改善维持在36个月。对语言没有主要影响。减肥手术可能会导致认知能力的持久改善。具有长期随访的前瞻性研究(例如,10年)应检查减肥手术是否可以减轻严重肥胖者的认知能力下降。
Bariatric surgery is associated with improved cognition and it is possible that such improvements are found at extended follow-ups. We hypothesized that cognitive improvement would be maintained 3 years post-bariatric surgery. Fifty bariatric patients were recruited from the Longitudinal Assessment of Bariatric Surgery parent project. Participants completed a computerized cognitive test battery to assess cognitive function at 12-weeks, 12-months, 24-months, and 36-months post-surgery. Repeated measures revealed main effects for attention, executive function, and memory. Attention improved up to 24-months and then slightly declined, though still fell within the average range at 36-months. Improvements in executive function reached its peak at 36-months post-surgery. Short-term improvements in memory were maintained at 36-months. No main effect emerged for language. Bariatric surgery may lead to lasting improvements in cognition. Prospective studies with extended follow-ups (e.g., 10 years) should examine whether bariatric surgery can attenuate cognitive decline in severely obese persons.
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