Small Indian mongooses and masked palm civets serve as new reservoirs of Bartonella henselae and potential sources of infection for humans.
Small Indian mongooses and masked palm civets serve as new reservoirs of Bartonella henselae and potential sources of infection for humans.
复制标题
DOI：
10.1111/1469-0691.12164
复制
发表时间：
2013-12
期刊：
影响因子：
--
通讯作者：
Maruyama S
中科院分区：
文献类型：
--
作者：
Sato S;Kabeya H;Shigematsu Y;Sentsui H;Une Y;Minami M;Murata K;Ogura G;Maruyama S
在日本的小印度猫鼬和果子狸中调查了巴尔通体属的患病率和遗传特性。从猫鼬和果子狸身上分别分离到15.9%（10/63）和2.0%（1/50）的汉赛巴尔通体（Bartonellahenselae）。猫鼬的菌血症水平范围为3.0 × 101至8.9 × 103 CFU/mL，果子狸的菌血症水平为7.0 × 103 CFU/mL。基于9个基因间间隔区的多间隔区分型（MST）分析导致检测到5种MST基因型（MST 8，14，37，58和59）的分离株，其与来自所有CSD患者和日本大部分猫的分离株的MST基因型一起分组在谱系1中。猫鼬MST 14是猫和人的优势基因型。这是首次报道分离到B。来自印度猫鼬和果子狸。在本研究中获得的数据表明，这些动物作为新的水库的B。henselae，并可能作为人类感染的潜在来源。
The prevalence and genetic properties of Bartonella species were investigated in small Indian mongooses and masked palm civets in Japan. Bartonella henselae, the causative agent of cat-scratch disease (CSD) was isolated from 15.9% (10/63) of the mongooses and 2.0% (1/50) of the masked palm civets, respectively. The bacteraemic level ranged from 3.0 × 101 to 8.9 × 103 CFU/mL in mongooses and was 7.0 × 103 CFU/mL in the masked palm civet. Multispacer typing (MST) analysis based on nine intergenic spacers resulted in the detection of five MST genotypes (MSTs 8, 14, 37, 58 and 59) for the isolates, which grouped in lineage 1 with MST genotypes of isolates from all CSD patients and most of the cats in Japan. It was also found that MST14 from the mongoose strains was the predominant genotype of cat and human strains. This is the first report on the isolation of B. henselae from small Indian mongooses and masked palm civets. The data obtained in the present study suggest that these animals serve as new reservoirs for B. henselae, and may play a role as potential sources of human infection.
登录
查看更多内容
影响因子：
1.2
作者：
Tei, Kazumi;Kato, Takuya;Kawakami, Eiichi
通讯作者：
Kawakami, Eiichi
DOI：
10.1196/annals.1374.080
发表时间：
2006-01-01
期刊：
CENTURY OF RICKETTSIOLOGY: EMERGING, REEMERGING RICKETTSIOSES, MOLECULAR DIAGNOSTICS, AND EMERGING VETERINARY RICKETTSIOSES
影响因子：
--
作者：
Chomel, Brtyno B.;Kasten, Rickie W.;Molia, Sophie
通讯作者：
Molia, Sophie
影响因子：
9.4
作者：
Heller, R;Artois, M;Piemont, Y
通讯作者：
Piemont, Y
影响因子：
4.4
作者：
Inoue, Kai;Maruyama, Soichi;Kawabata, Hiroki
通讯作者：
Kawabata, Hiroki
影响因子：
56.9
作者：
Guan, Y;Zheng, BJ;Poon, LLM
通讯作者：
Poon, LLM