Cytotoxic T cell specificity for respiratory syncytial virus proteins: fusion protein is an important target antigen.
Cytotoxic T cell specificity for respiratory syncytial virus proteins: fusion protein is an important target antigen.
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细胞毒性T细胞对呼吸道合胞病毒蛋白的特异性:融合蛋白是重要的靶抗原。
DOI:
10.1099/0022-1317-68-8-2177
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发表时间:
1987
期刊:
影响因子:
--
通讯作者:
Askonas,BA
中科院分区:
文献类型:
--
作者:
Pemberton,RM;Cannon,MJ;Openshaw,PJ;Ball,LA;Wertz,GW;Askonas,BA
We examined the specificity of BALB/c cytotoxic T (Tc) cells for respiratory syncytial virus (RSV) components, using recombinant vaccinia viruses (VV) coding for several individual RSV proteins. We found that immunization with the different VVs yielded the following Tcmemory cell populations: high levels of RSV-specific Tccells were induced with the fusion protein VV, but low levels were induced with VV coding for the RSV nucleoprotein. Tccell recognition of attachment glycoprotein, part of the matrix molecule or 1A internal protein was poor. While high levels of fusion protein- specific Tccells were induced by the fusion protein VV, they showed poor crossreactivity between the A2 and 8/60 RSV strains compared with Tccells primed by RSV infection.
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DOI:
--
发表时间:
1981
期刊:
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine
影响因子:
--
作者:
B. Fernie;E. Ford;J. Gerin
通讯作者:
J. Gerin
DOI:
10.1073/pnas.82.6.1785
发表时间:
1985-01-01
影响因子:
11.1
作者:
YEWDELL, JW;BENNINK, JR;MOSS, B
通讯作者:
MOSS, B
DOI:
--
发表时间:
1982
期刊:
Journal of immunology (Baltimore, Md. : 1950)
影响因子:
--
作者:
Finberg,R;Spriggs,DR;Fields,BN
通讯作者:
Fields,BN
影响因子:
3.1
作者:
E. Walsh;J. Schlesinger;M. W. Brandriss
通讯作者:
M. W. Brandriss
影响因子:
3.1
作者:
TAYLOR, G;STOTT, EJ;COLLINS, AP
通讯作者:
COLLINS, AP