Female Fertility and Environmental Pollution.
Female Fertility and Environmental Pollution.
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DOI：
10.3390/ijerph17238802
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发表时间：
2020-11-26
影响因子：
--
通讯作者：
Cecconi S
中科院分区：
文献类型：
--
作者：
Canipari R;De Santis L;Cecconi S
我们世界的现实情况表明，它到处都受到严重污染。沿海地区和海洋受到农业肥料、粪肥径流、污水和工业排放的污染，大量废塑料漂浮在周围，影响海洋生物。陆地生态系统受到重金属和有机化学品的污染，这些物质可被作物吸收并在作物中积累，地下水受到未经处理的工业排放物的严重污染。由于致命的颗粒物可以飘得很远，空气质量差已成为一个重大的全球性问题，而且不仅仅是主要工业化城市的问题。其后果是严重损害我们的生态系统和生物多样性，并增加退化性或人为疾病。在这方面，已经证明，环境污染损害所有哺乳动物物种的生育能力。最坏的结果是观察到女性，因为生殖细胞的数量存在于卵巢中是固定的在胎儿的生活，细胞是不可再生的。这意味着任何影响荷尔蒙平衡和/或生殖器官的污染物都不可避免地会损害生殖能力。这种下降将产生重大的社会和经济后果，再也不能忽视。
A realistic picture of our world shows that it is heavily polluted everywhere. Coastal regions and oceans are polluted by farm fertilizer, manure runoff, sewage and industrial discharges, and large isles of waste plastic are floating around, impacting sea life. Terrestrial ecosystems are contaminated by heavy metals and organic chemicals that can be taken up by and accumulate in crop plants, and water tables are heavily contaminated by untreated industrial discharges. As deadly particulates can drift far, poor air quality has become a significant global problem and one that is not exclusive to major industrialized cities. The consequences are a dramatic impairment of our ecosystem and biodiversity and increases in degenerative or man-made diseases. In this respect, it has been demonstrated that environmental pollution impairs fertility in all mammalian species. The worst consequences are observed for females since the number of germ cells present in the ovary is fixed during fetal life, and the cells are not renewable. This means that any pollutant affecting hormonal homeostasis and/or the reproductive apparatus inevitably harms reproductive performance. This decline will have important social and economic consequences that can no longer be overlooked.
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影响因子：
4
作者：
Burton GJ;Jauniaux E
通讯作者：
Jauniaux E
DOI：
10.1080/10590501.2012.705159
发表时间：
2012
期刊：
Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews
影响因子：
--
作者：
Aquino NB;Sevigny MB;Sabangan J;Louie MC
通讯作者：
Louie MC
锌缺乏和砷暴露对斑马鱼（Danio Rerio）发育的组合作用。
影响因子：
3.7
作者：
Beaver LM;Truong L;Barton CL;Chase TT;Gonnerman GD;Wong CP;Tanguay RL;Ho E
通讯作者：
Ho E
影响因子：
4
作者：
Alviggi C;Guadagni R;Conforti A;Coppola G;Picarelli S;De Rosa P;Vallone R;Strina I;Pagano T;Mollo A;Acampora A;De Placido G
通讯作者：
De Placido G
DOI：
10.1016/j.reprotox.2010.01.003
发表时间：
2010-06
期刊：
Reproductive toxicology (Elmsford, N.Y.)
影响因子：
--
作者：
Bloom MS;Parsons PJ;Steuerwald AJ;Schisterman EF;Browne RW;Kim K;Coccaro GA;Conti GC;Narayan N;Fujimoto VY
通讯作者：
Fujimoto VY