Complete nucleotide sequence of the topA gene encoding Escherichia coli DNA topoisomerase I.
Complete nucleotide sequence of the topA gene encoding Escherichia coli DNA topoisomerase I.
复制标题
编码大肠杆菌 DNA 拓扑异构酶 I 的 topA 基因的完整核苷酸序列。
DOI:
10.1016/0022-2836(86)90129-4
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发表时间:
1986
影响因子:
5.6
通讯作者:
Wang,JC
中科院分区:
文献类型:
--
作者:
Tse-Dinh,YC;Wang,JC
The nucleotide sequence of a 4071 base-pair long segment containing the genetopA encoding Escherichia coliDNA topoisomerase I and its flanking regions has been determined. The gene encodes a total of 864 amino acids from the ATG start to a TAA termination codon, of which the first f-Met appears to be removed after translation; the calculated molecular weight of the translated protein is 97,413. Mapping of promoters by deletion of sequences upstream from the ATG initiation codon indicates the existence of at least two promoters that direct transcription intotopA.
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影响因子:
14.9
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通讯作者:
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64.5
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J. Steitz
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通讯作者:
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