ISCEV extended protocol for the photopic negative response (PhNR) of the full-field electroretinogram.
ISCEV extended protocol for the photopic negative response (PhNR) of the full-field electroretinogram.
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DOI：
10.1007/s10633-018-9638-x
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发表时间：
2018-06
期刊：
影响因子：
--
通讯作者：
Viswanathan S
中科院分区：
文献类型：
--
作者：
Frishman L;Sustar M;Kremers J;McAnany JJ;Sarossy M;Tzekov R;Viswanathan S
国际临床视觉电生理学会（ISCEV）的全视野视网膜电图（ERG）标准描述了一个最低限度的程序，但鼓励更广泛的测试。该ISCEV扩展方案描述了ERG标准的扩展，即光适应闪光ERG的明视负响应（PhNR），作为一种被该领域专家广泛接受的成熟技术。PhNR是b波之后的缓慢负向波，其提供关于视网膜神经节细胞及其轴突的功能的信息。PhNR可以在影响最内层视网膜的疾病中减少，包括青光眼和其他形式的视神经病变。本文件基于现有文献，提供了记录和分析PhNR响应短暂闪光的方案。该协议包括全场刺激，记录的频率带宽，其中下限不超过0.3 Hz，和光谱窄带刺激，具体地说，红色闪光棒饱和蓝色背景。建议的闪光强度范围最高可达并包括引起最大振幅PhNR所需的最小值。这种用于记录PhNR的扩展方案提供了可以添加到标准ERG测试中的广义视网膜神经节细胞功能的简单测试。
The International Society for Clinical Electrophysiology of Vision (ISCEV) Standard for full-field electroretinography (ERG) describes a minimum procedure, but encourages more extensive testing. This ISCEV extended protocol describes an extension to the ERG Standard, namely the photopic negative response (PhNR) of the light-adapted flash ERG, as a well-established technique that is broadly accepted by experts in the field. The PhNR is a slow negative-going wave after the b-wave that provides information about the function of retinal ganglion cells and their axons. The PhNR can be reduced in disorders that affect the innermost retina, including glaucoma and other forms of optic neuropathy. This document, based on existing literature, provides a protocol for recording and analyzing the PhNR in response to a brief flash. The protocol includes full-field stimulation, a frequency bandwidth of the recording in which the lower limit does not exceed 0.3 Hz, and a spectrally narrowband stimulus, specifically, a red flash on a rod saturating blue background. Suggested flash strengths cover a range up to and including the minimum required to elicit a maximum amplitude PhNR. This extended protocol for recording the PhNR provides a simple test of generalized retinal ganglion cell function that could be added to standard ERG testing.
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DOI：
10.1007/s00417-008-0791-x
发表时间：
2008-07-01
影响因子：
2.7
作者：
Shinoda, Kei;Yamada, Kisaburo;Nakatsuka, Kazuo
通讯作者：
Nakatsuka, Kazuo
影响因子：
5.5
作者：
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影响因子：
1.4
作者：
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DOI：
10.1007/s10633-017-9591-0
发表时间：
2017-08
期刊：
Documenta ophthalmologica. Advances in ophthalmology
影响因子：
--
作者：
Joshi NR;Ly E;Viswanathan S
通讯作者：
Viswanathan S
影响因子：
4.4
作者：
Machida, Shigeki;Toba, Yoshiharu;Kurosaka, Daijiro
通讯作者：
Kurosaka, Daijiro