Indocyanine green-incorporating nanoparticles for cancer theranostics.

Indocyanine green-incorporating nanoparticles for cancer theranostics.
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DOI:
10.7150/thno.22872
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发表时间:
2018
期刊:
影响因子:
12.4
通讯作者:
Liang X
Liang X
中科院分区:
医学1区
文献类型:
--
作者:
Wang H;Li X;Tse BW;Yang H;Thorling CA;Liu Y;Touraud M;Chouane JB;Liu X;Roberts MS;Liang X

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Indocyanine green (ICG) is a near-infrared dye that has been used in the clinic for retinal angiography, and defining cardiovascular and liver function for over 50 years. Recently, there has been an increasing interest in the incorporation of ICG into nanoparticles (NPs) for cancer theranostic applications. Various types of ICG-incorporated NPs have been developed and strategically functionalised to embrace multiple imaging and therapeutic techniques for cancer diagnosis and treatment. This review systematically summaries the biodistribution of various types of ICG-incorporated NPs for the first time, and discusses the principles, opportunities, limitations, and application of ICG-incorporated NPs for cancer theranostics. We believe that ICG-incorporated NPs would be a promising multifunctional theranostic platform in oncology and facilitate significant advancements in this research-active area.
近红外染料负载磁性纳米粒子作为增强肿瘤成像的光声造影剂
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