Exploring outcome measures for exercise intervention in people with Parkinson's disease.

Exploring outcome measures for exercise intervention in people with Parkinson's disease.
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DOI:
10.1155/2013/572134
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发表时间:
2013
期刊:
Parkinson's disease
影响因子:
--
通讯作者:
Horak FB
Horak FB
中科院分区:
其他
文献类型:
--
作者:
King LA;Salarian A;Mancini M;Priest KC;Nutt J;Serdar A;Wilhelm J;Schlimgen J;Smith M;Horak FB

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背景人们普遍认为,运动可以改善帕金森病(PD)患者的活动能力。然而,很难确定一种特定类型的运动是否最有效。本研究的目的是确定哪些结果指标对运动干预敏感,并探讨两种不同的运动计划对改善PD患者活动能力的影响。方法.参与者被随机分为敏捷靴子训练营(ABC)或跑步机训练;每周4次,持续4周。结果指标按照国际功能/残疾分类(ICF)进行分组。为了确定对运动的反应性,我们计算了标准化反应均值。t检验用于比较每种锻炼计划的相对益处。结果运动后,结构/功能水平的五个变量中有四个发生了变化:转身持续时间(P = 0.03)、步幅速度(P = 0.001)、手臂峰值速度(P = 0.001)和步态期间的躯干水平ROM(P = 0.02)。两种干预措施的大多数指标都有类似的改善。ABC组中检测到组间差异的唯一变量是姿势摇摆(F = 4.95; P = 0.03)。结论ICF身体结构/功能水平的结果测量在检测运动后的变化和揭示干预措施之间的改善差异方面最有效。
Background. It is widely believed that exercise improves mobility in people with Parkinson's disease (PD). However, it is difficult to determine whether a specific type of exercise is the most effective. The purpose of this study was to determine which outcome measures were sensitive to exercise intervention and to explore the effects of two different exercise programs for improving mobility in patients with PD. Methods. Participants were randomized into either the Agility Boot Camp (ABC) or treadmill training; 4x/week for 4 weeks. Outcome measures were grouped by the International Classification of Function/Disability (ICF). To determine the responsiveness to exercise, we calculated the standardized response means. t-tests were used to compare the relative benefits of each exercise program. Results. Four of five variables at the structure/function level changed after exercise: turn duration (P = 0.03), stride velocity (P = 0.001), peak arm speed (P = 0.001), and horizontal trunk ROM during gait (P = 0.02). Most measures improved similarly for both interventions. The only variable that detected a difference between groups was postural sway in ABC group (F = 4.95; P = 0.03). Conclusion. Outcome measures at ICF body structure/function level were most effective at detecting change after exercise and revealing differences in improvement between interventions.
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