Pharmaceutical Values of Calycosin: One Type of Flavonoid Isolated from Astragalus.

Pharmaceutical Values of Calycosin: One Type of Flavonoid Isolated from Astragalus.
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DOI:
10.1155/2021/9952578
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发表时间:
2021
期刊:
Evidence-based complementary and alternative medicine : eCAM
影响因子:
--
通讯作者:
Wen Z
Wen Z
中科院分区:
其他
文献类型:
--
作者:
Gong G;Zheng Y;Yang Y;Sui Y;Wen Z

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黄芪是中国流行的中药材,可用于治疗多种疾病。它含有多种化学活性成分,如皂苷、类黄酮和多糖。植物衍生的生物活性化学物质被认为是天然、安全和有益的。在无数被植物鉴定和分离的分子中,类黄酮被报道对人类健康有积极的影响。毛蕊异黄酮是该药用植物中最重要的活性类黄酮物质。近年来,有报道称毛蕊异黄酮具有抗癌、抗氧化、免疫调节和雌激素样特性。本文收集了近年来有关毛蕊异黄酮的相关文献,对其潜在的药理特性及其作用机制进行了综述,为今后的临床研究提供了坚实的基础。
Astragalus is a popular Materia Medica in China, and it could be applied in the treatment of various diseases. It contains a variety of chemically active ingredients, such as saponins, flavonoids, and polysaccharides. Plant-derived bioactive chemicals are considered natural, safe, and beneficial. Among the infinite plant-identified and isolated molecules, flavonoids have been reported to have positive effects on human health. Calycosin is the most important active flavonoid substance identified predominantly within this medicinal plant. In recent years, calycosin has been reported to have anticancer, antioxidative, immune-modulatory, and estrogenic-like properties. This review collected recent relevant literatures on calycosin and summarized its potential pharmaceutical properties and working mechanism involved, which provided solid basis for future clinical research.
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