Genetic analysis of olfactory behavior in Drosophila: a new screen yields the ota mutants.

Genetic analysis of olfactory behavior in Drosophila: a new screen yields the ota mutants.
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果蝇嗅觉行为的遗传分析:新筛选产生 ota 突变体。

DOI:
10.1093/genetics/123.2.315
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发表时间:
1989
期刊:
影响因子:
3.3
通讯作者:
Carlson,J
Carlson,J
中科院分区:
生物学2区
文献类型:
--
作者:
Woodard,C;Huang,T;Sun,H;Helfand,SL;Carlson,J

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描述了一种测量果蝇嗅觉反应的简单方法,并描述了它所测量的行为特征。该试验用于筛选嗅觉功能缺陷的x连锁突变体。分离并鉴定了6个ota突变体(ota =嗅觉陷阱异常)。其中四个突变体在另一种化学感觉行为中也被发现异常。两种突变表型扩展到包括另一个感觉系统:它们在视觉系统生理上有缺陷。然而,在大纤维系统生理学测试中,所有人都是正常的。其中两个突变是显性突变,而隐性突变定义了两个互补群。绘制了代表每个互补组的突变,以及一个显性突变。对于具有视觉系统生理缺陷的突变体,视觉缺陷显示与嗅觉表型共分离。
A simple means of measuring Drosophila olfactory response is described, and the behavior which it measures is characterized. The assay was used to screen for X-linked mutants defective in olfactory function. Six ota mutants were isolated and characterized (ota = olfactory trap abnormal). Four of the mutants were found to be abnormal in another chemosensory behavior as well. Two of the mutant phenotypes extend to include another sensory system: they are defective in visual system physiology. All were normal, however, in a test of giant fiber system physiology. Two of the mutations are dominant, and the recessive mutations define two complementation groups. Mutations representing each complementation group, as well as one of the dominant mutations, were mapped. For the mutants with defective visual system physiology, the visual defects were shown to cosegregate with olfactory phenotypes.
DOI: 10.1016/0020-7322(84)90032-1
发表时间: 1984
期刊: International Journal of Insect Morphology & Embryology
影响因子: --
作者:
S. Venkatesh;R. N. Singh
通讯作者: R. N. Singh
触角突变体的分离及其在果蝇嗅觉遗传学中的应用
DOI: --
发表时间: 1989
期刊:
影响因子: --
作者:
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通讯作者: J. Carlson
影响因子: 11.1
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期刊: Basic life sciences
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