Early 24-hour blood pressure elevation in normotensive subjects with parental hypertension.
Early 24-hour blood pressure elevation in normotensive subjects with parental hypertension.
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患有父母高血压的血压正常受试者早期 24 小时血压升高。
DOI：
10.1161/01.hyp.16.5.491
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发表时间：
1990
期刊：
影响因子：
8.3
通讯作者：
G. Mancia
中科院分区：
文献类型：
--
作者：
A. Ravogli;S. Trazzi;A. Villani;E. Mutti;C. Cuspidi;L. Sampieri;L. Ambroggi;G. Parati;A. Zanchetti;G. Mancia
据报道，有父母高血压家族史的受试者在高血压前期阶段的诊室血压略高。然而，这是否反映了对血压测量的过度反应或更持久的血压升高，尚不清楚。在本研究中，测量了 15 名父母均为高血压患者的血压正常受试者（FH++）、15 名父母均为高血压患者的血压正常受试者（FH(+)-）和 15 名父母均不患有高血压的血压正常受试者（FH--）的血压；在三组中，受试者的年龄、性别和体重指数相匹配。这些测量是在各种实验室压力源和长时间休息期间以及 24 小时期间（动态血压监测）期间在办公室进行的。 FH++ 组的诊室血压高于 FH-- 组（p 小于 0.05）。两组对实验室压力源的升压反应相似，但 FH++ 组的长时间静息血压和 24 小时血压高于 FH-- 组；收缩压的差异始终显着（p 小于 0.05）。 FH++ 组的左心室质量指数（超声心动图检查）也高于 FH-- 组（p 小于 0.01）。 FH(+)-组的血压值和超声心动图值倾向于介于其他两组之间。因此，有父母高血压家族史的高血压前期个体表现出的较高血压并不反映对压力的过度反应，而是反映早期永久性血压升高。（摘要截断为250字）
Subjects with a family history of parental hypertension are reported to have a slightly higher office blood pressure in the prehypertensive stage. Whether this reflects a hyperreactivity to blood pressure measurement or a more permanent blood pressure elevation, however, is not known. In the present study, blood pressure was measured in 15 normotensive subjects whose parents are both hypertensive (FH++), 15 normotensive subjects with one hypertensive parent (FH(+)-), and 15 normotensive subjects whose parents are not hypertensive (FH--); among the three groups, subjects were matched for age, sex, and body mass index. The measurements were made in the office during a variety of laboratory stressors and during a prolonged resting period, and for a 24-hour period (ambulatory blood pressure monitoring). Office blood pressure was higher in the FH++ group than in the FH-- group (p less than 0.05). The pressor responses to laboratory stressors were similar in the two groups, but the FH++ group had higher prolonged resting and 24-hour blood pressure than the FH-- group; the difference was always significant (p less than 0.05) for systolic blood pressure. The FH++ group also had a greater left ventricular mass index (on echocardiographic examination) than the FH-- group (p less than 0.01). The blood pressure values and echocardiographic values of the FH(+)- group tended to be between those of the other two groups. Thus, the higher blood pressure shown by individuals in the prehypertensive stage with a family history of parental hypertension does not reflect a hyperreactivity to stress but an early permanent blood pressure elevation.(ABSTRACT TRUNCATED AT 250 WORDS)
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高血压父母的孩子在精神压力期间前臂血流量增强。
DOI：
10.1161/01.hyp.10.5.544
发表时间：
1987
期刊：
Hypertension (Dallas, Tex. : 1979)
影响因子：
--
作者：
Anderson,EA;Mahoney,LT;Lauer,RM;Clarke,WR
通讯作者：
Clarke,WR
父母高血压和心血管对认知和等长挑战的反应。
影响因子：
3.7
作者：
Manuck,SB;Proietti,JM
通讯作者：
Proietti,JM
影响因子：
37.8
作者：
DEVEREUX, RB;PICKERING, TG;LARAGH, JH
通讯作者：
LARAGH, JH
健康年轻人父母高血压和心血管对压力的反应。
影响因子：
3.7
作者：
Hastrup,JL;Light,KC;Obrist,PA
通讯作者：
Obrist,PA