Development of a Psychosocial Intervention to Promote Treatment Adherence in Patients with Bipolar Disorder at Risk of Cardiovascular Disease.
Development of a Psychosocial Intervention to Promote Treatment Adherence in Patients with Bipolar Disorder at Risk of Cardiovascular Disease.
复制标题
开发心理社会干预以促进有心血管疾病风险的双相情感障碍患者的治疗依从性。
DOI：
10.3390/jcm10245890
复制
发表时间：
2021-12-15
影响因子：
3.9
通讯作者：
Otero W
中科院分区：
文献类型：
--
作者：
Ralat SI;Alicea-Cuprill G;Arroyo Y;Otero W
不坚持治疗是影响双相情感障碍(BD)患者成功治疗的一个严重问题。这项研究的目的是试行一种心理社会干预措施(由该团队先前开发)，旨在提高BD患者对针对心血管疾病(CVD)危险因素的药物和健康行为的依从性。采用开放的单组设计来评估干预的可行性和可接受性。参与者有BD、I/II型或未指明的危险因素，以及心血管疾病的危险因素。采取了基线人口统计措施。我们还获得了与自我报告的精神药物依从性、抑郁和躁狂症状以及药房记录的前后变化相关的初步效应大小。在基线时，29%的参与者报告最近坚持接受精神药物治疗。共有71%的参与者完成了干预。在服药依从性、对药物的态度和躁狂症状方面，患者在服药依从性、对药物的态度和躁狂症状方面均有中等和较大的改善(Cohen‘s d=0.52-0.92)。参与者报告对干预措施的满意度很高。对有心血管疾病风险的波多黎各BD患者进行文化敏感的心理社会干预被认为是可行和可接受的。在这项小规模的初步研究中，关键结果得到了改善。需要在更大的样本量下进行进一步的研究。
Nonadherence to treatment is a serious concern that affects the successful management of bipolar disorder (BD) patients. The aim of this study was to pilot test a psychosocial intervention (previously developed by this team) intended to increase adherence to medication and health behaviors targeting cardiovascular disease (CVD) risk factors in BD patients. An open, single-group design was used to assess the feasibility and acceptability of the intervention. The participants had BD, type I/II or unspecified, and CVD risk factors. Baseline demographic measures were taken. We also obtained preliminary effect sizes related to pre-post changes on measures of self-reported adherence to psychiatric medication, depressive and manic symptoms, and pharmacy records. At baseline, 29% of the participants reported recent adherence to psychiatric medications. A total of 71% of the participants completed the intervention. Pre-post improvements by medium and large effect sizes (Cohen’s d = 0.52–0.92) were seen in medication adherence, attitudes toward medication, and mania symptoms. The participants reported high levels of satisfaction with the intervention. A culturally sensitive psychosocial intervention for Puerto Rican BD patients who are at risk of CVD was found to be feasible and acceptable. Improvements in the key outcomes were seen in this small, preliminary study. Further research is needed with a larger sample size.
登录
查看更多内容
DOI：
10.3390/ijerph18041694
发表时间：
2021-02-10
影响因子：
--
作者：
Ralat SI
通讯作者：
Ralat SI
影响因子：
3.9
作者：
Colom, F;Vieta, E;Salamero, M
通讯作者：
Salamero, M
影响因子：
2.3
作者：
Bernal, G;Sáez-Santiago, E
通讯作者：
Sáez-Santiago, E
影响因子：
2.7
作者：
Ralat, Sandra I.;Depp, Colin A.;Bernal, Guillermo
通讯作者：
Bernal, Guillermo
DOI：
10.1093/ijnp/pyx032
发表时间：
2017-08-01
期刊：
The international journal of neuropsychopharmacology
影响因子：
--
作者：
Solé B;Jiménez E;Torrent C;Reinares M;Bonnin CDM;Torres I;Varo C;Grande I;Valls E;Salagre E;Sanchez-Moreno J;Martinez-Aran A;Carvalho AF;Vieta E
通讯作者：
Vieta E