Using the MMSE-2 to Measure Cognitive Deterioration in a Sample of Psychiatric Patients Living in Puerto Rico.
Using the MMSE-2 to Measure Cognitive Deterioration in a Sample of Psychiatric Patients Living in Puerto Rico.
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DOI：
10.3390/ijerph18041694
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发表时间：
2021-02-10
影响因子：
--
通讯作者：
Ralat SI
中科院分区：
文献类型：
--
作者：
Ralat SI
精神疾病患者通常有认知障碍。在情绪和/或精神障碍患者中已经发现了几种缺陷。我们假设双相情感障碍（BD）、重度抑郁障碍（MDD）和分裂情感障碍（SAD）患者的恶化程度存在差异。最小精神状态检查，版本2 (MMSE-2)，被用于160例精神病患者的样本来测量认知障碍。本研究的目的如下：(1)分析诊断为双相障碍、重度抑郁症和SAD的患者在认知功能恶化方面的差异；(2)探讨基于文化程度等变量的项目难度和分界点对我国精神科人群有显著意义。分类变量采用描述性统计。此外，对连续因变量进行了Bonferroni事后检验和协方差分析（ANCOVA）。经几个协变量调整后的精神病学诊断和受教育年限被证明是显著的。取第25百分位作为分界点。采用均数和卡方检验分析每个项目的难度。51%的SAD患者、31%的双相障碍患者和18%的重度抑郁症患者存在认知功能减退。
Patients with psychiatric disorders often have cognitive impairment. Several deficits have been recognized in patients with mood and/or psychotic disorders. We hypothesized that differences in the levels of deterioration exist between patients with bipolar disorder (BD), major depressive disorder (MDD), and schizoaffective disorder (SAD). The mini-mental state examination, version 2 (MMSE-2), was used with a sample of 160 psychiatric patients to measure cognitive impairment. The aims of this study were as follows: (1) To characterize the differences in cognitive deterioration among patients diagnosed with BD, MDD, or SAD; (2) to explore item difficulty and cutoff points based on the educational level and other variables which are significant for our psychiatric population. Descriptive statistics were used for categorical variables. In addition, a Bonferroni post hoc test and an analysis of covariance (ANCOVA) for the continuous dependent variable were performed. Psychiatric diagnosis and years of education adjusted by several covariates proved to be significant. The 25th percentile were obtained to establish the cutoff points. Each item’s difficulty was analyzed using means and chi-square tests. Cognitive deterioration was found in 51% of the patients with SAD, in 31% with BD, and in 18% with MDD.
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影响因子：
6.9
作者：
Amann, B.;Gomar, J. J.;Pomarol-Clotet, E.
通讯作者：
Pomarol-Clotet, E.
影响因子：
11.3
作者：
Ong, Hui Lin;Subramaniam, Mythily;Chong, Siow Ann
通讯作者：
Chong, Siow Ann
影响因子：
5.4
作者：
Gildengers AG;Butters MA;Chisholm D;Anderson SJ;Begley A;Holm M;Rogers JC;Reynolds CF 3rd;Mulsant BH
通讯作者：
Mulsant BH
影响因子：
1.2
作者：
Hahn, Lisa;Kessler, Josef
通讯作者：
Kessler, Josef
DOI：
10.1093/ijnp/pyx032
发表时间：
2017-08-01
期刊：
The international journal of neuropsychopharmacology
影响因子：
--
作者：
Solé B;Jiménez E;Torrent C;Reinares M;Bonnin CDM;Torres I;Varo C;Grande I;Valls E;Salagre E;Sanchez-Moreno J;Martinez-Aran A;Carvalho AF;Vieta E
通讯作者：
Vieta E