Relationship between reproductive success and male plasma vitellogenin concentrations in cunner, Tautogolabrus adspersus.
Relationship between reproductive success and male plasma vitellogenin concentrations in cunner, Tautogolabrus adspersus.
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DOI：
10.1289/ehp.5531
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发表时间：
2003-01
影响因子：
10.4
通讯作者：
Zaroogian GE
中科院分区：
文献类型：
--
作者：
Mills LJ;Gutjahr-Gobell RE;Horowitz DB;Denslow ND;Chow MC;Zaroogian GE
卵黄蛋白原（一种卵黄蛋白前体）的基因在雄鱼中通常是沉默的，但可以被雌激素诱导。因此，雄鱼卵黄蛋白原的产生已成为水生环境中暴露于外源性雌激素或雌激素模拟物的广泛使用的指标。该指标预测鱼类生殖成功的影响的效用尚不清楚，因为男性血浆卵黄蛋白原和生殖终点之间的关系，在男性和女性的鱼的信息是有限的。在本文报道的研究中，我们调查了雄性血浆卵黄蛋白原的存在是否是成熟鱼类繁殖成功率降低的可靠指标。成年和性成熟的男性和女性cunner（Taautogolabrus adspersus）暴露于17 β-雌二醇，炔雌醇，或雌酮，三种甾体雌激素，引起的卵黄反应。收集并汇总了关于产蛋量、卵子活力、卵子生育力、精子活力和雄性血浆卵黄蛋白原浓度的数据。所有雄性动物（包括血浆卵黄蛋白原水平超过300 mg/mL的两只）均产生活动精子。无论是百分比受精卵，也不百分比可行的鸡蛋生产的繁殖活跃的鱼表现出显着的相关性与男性血浆卵黄蛋白原浓度。雄性性腺指数和雌性平均日产卵量与雄性血浆卵黄蛋白原浓度呈显著但微弱的负相关。结果表明，男性血浆卵黄蛋白原表达不是一个可靠的指标，男性生殖功能障碍的成年cunner暴露于雌激素2-8周，在他们的生殖季节，至少在有关的能力，以产生活动的精子或受精卵。雄性血浆卵黄蛋白原表达可作为雌激素暴露引起的雌性生殖功能降低的指标。
The gene for vitellogenin, an egg yolk protein precursor, is usually silent in male fish but can be induced by estrogen exposure. For this reason, vitellogenin production in male fish has become a widely used indicator of exposure to exogenous estrogens or estrogen mimics in the aquatic environment. The utility of this indicator to predict impacts on fish reproductive success is unclear because information on the relationship between male plasma vitellogenin and reproductive end points in male and female fish is limited. In the research reported in this article, we investigated whether the presence of male plasma vitellogenin is a reliable indicator of decreased reproductive success in mature fish. Adult and sexually mature male and female cunner (Tautogolabrus adspersus) were exposed to 17ss-estradiol, ethynylestradiol, or estrone, three steroidal estrogens that elicit the vitellogenic response. Data were gathered and pooled on egg production, egg viability, egg fertility, sperm motility, and male plasma vitellogenin concentrations. All males, including two with plasma vitellogenin levels exceeding 300 mg/mL, produced motile sperm. Neither percent fertile eggs nor percent viable eggs produced by reproductively active fish demonstrated a significant correlation with male plasma vitellogenin concentrations. Male gonadosomatic index and average daily egg production by females showed significant, but weak, negative correlation with male plasma vitellogenin concentrations. Results suggest that male plasma vitellogenin expression is not a reliable indicator of male reproductive dysfunction in adult cunner exposed to estrogens for 2-8 weeks during their reproductive season, at least in relation to capacity to produce motile sperm or fertilize eggs. Male plasma vitellogenin expression may serve as an indicator of reduced female reproductive function caused by estrogen exposure.
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影响因子：
3.3
作者：
Christiansen, LB;Pedersen, KL;Bjerregaard, P
通讯作者：
Bjerregaard, P
影响因子：
3.3
作者：
Christiansen, T;Korsgaard, B;Jespersen, A
通讯作者：
Jespersen, A
影响因子：
4.5
作者：
Gimeno, S;Komen, H;Bowmer, T
通讯作者：
Bowmer, T
影响因子：
2.9
作者：
Reis-Henriques, MA;Cruz, MM;Pereira, JO
通讯作者：
Pereira, JO
影响因子：
11.4
作者：
Rodgers-Gray, TP;Jobling, S;Tyler, CR
通讯作者：
Tyler, CR