Current strategies to improve the bioactivity of PEEK.
Current strategies to improve the bioactivity of PEEK.
复制标题
当前提高 PEEK 生物活性的策略
DOI:
10.3390/ijms15045426
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发表时间:
2014-03-28
影响因子:
5.6
通讯作者:
Tang T
中科院分区:
文献类型:
--
作者:
Ma R;Tang T
The synthetic thermoplastic polymer polyetheretherketone (PEEK) is becoming a popular component of clinical orthopedic and spinal applications, but its practical use suffers from several limitations. Although PEEK is biocompatible, chemically stable, radiolucent and has an elastic modulus similar to that of normal human bone, it is biologically inert, preventing good integration with adjacent bone tissues upon implantation. Recent efforts have focused on increasing the bioactivity of PEEK to improve the bone-implant interface. Two main strategies have been used to overcome the inert character of PEEK. One approach is surface modification to activate PEEK through surface treatment alone or in combination with a surface coating. Another strategy is to prepare bioactive PEEK composites by impregnating bioactive materials into PEEK substrate. Researchers believe that modified bioactive PEEK will have a wide range of orthopedic applications.
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DOI:
10.1007/s10856-005-2539-z
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