High validity of mother-reported use of antiasthmatics among children: a comparison with a population-based prescription database.
High validity of mother-reported use of antiasthmatics among children: a comparison with a population-based prescription database.
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DOI：
10.1016/j.jclinepi.2010.10.014
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发表时间：
2011-08
影响因子：
7.2
通讯作者：
Nystad, Wenche
中科院分区：
文献类型：
--
作者：
Furu, Kari;Karlstad, Oystein;Skurtveit, Svetlana;Haberg, Siri E.;Nafstad, Per;London, Stephanie J.;Nystad, Wenche
检查…的有效性：1）母亲问卷报告的儿童使用抗哮喘药的处方数据库作为参考标准，2）分发抗哮喘药作为衡量哮喘的母亲报告的儿童哮喘作为参考标准。挪威母亲和儿童队列研究（MoBa）中的3394名7岁儿童与挪威处方数据库（NorPD）相关联。母亲报告的两个孩子的使用抗哮喘药在前一年和哮喘的存在进行了比较，分发抗哮喘药的数据。2056名母亲回答并报告了前一年使用抗哮喘药的情况，147名儿童中有125名使用了抗哮喘药（敏感性85.0%）。在1909名没有分发抗哮喘药的儿童中，1848名没有母亲使用抗哮喘药的报告（特异性96.8%）。母亲报告133名儿童（占2056名儿童的6.5%）患有哮喘，其中122名（5.9%）经医生证实。在这122例患者中，98例在前一年接受了抗哮喘药物治疗（敏感性80.3%）。只有1.2%的未报告哮喘的儿童被分配抗哮喘药。7岁儿童中母亲报告的前一年使用抗哮喘药的情况高度有效。当疾病数据不可用时，分发的抗哮喘药将是当前哮喘存在的有用代理。
To examine the validity of: 1) maternal questionnaire report of children's use of anti-asthmatics using a prescription database as the reference standard, 2) dispensed anti-asthmatics as a measure of asthma using maternal report of children's asthma as the reference standard. 3394 children in the Norwegian Mother and Child Cohort Study (MoBa) aged seven were linked to the Norwegian Prescription Database (NorPD). Maternal report of both children's use of anti-asthmatics during the preceding year and of the presence of asthma was compared with data on dispensed anti-asthmatics. 2056 mothers responded and reported use of anti-asthmatics the previous year in 125 of 147 children who had been dispensed anti-asthmatics (sensitivity 85.0%). Of 1909 children with no dispensed anti-asthmatics, 1848 had no maternal report of anti-asthmatic use (specificity 96.8%). Mothers reported current asthma in 133 (6.5% of 2056) children, including 122 (5.9%) reported as verified by a doctor. Of these 122, 98 had been dispensed anti-asthmatics during the preceding year (sensitivity 80.3%). Only 1.2% of the children without reported asthma were dispensed anti-asthmatics. Mother-reported use of anti-asthmatics during the previous year among 7 year old children is highly valid. Dispensed anti-asthmatics would be a useful proxy for the presence of current asthma when disease data are not available.
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影响因子：
24.3
作者：
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通讯作者：
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