Lexical-semantic search related to side of onset and putamen volume in Parkinson's disease.

Lexical-semantic search related to side of onset and putamen volume in Parkinson's disease.
复制标题

DOI:
10.1016/j.bandl.2020.104841
复制
发表时间:
2020-10
期刊:
影响因子:
2.5
通讯作者:
Huang X
Huang X
中科院分区:
心理学3区
文献类型:
--
作者:
Wagner D;Eslinger PJ;Sterling NW;Du G;Lee EY;Styner M;Lewis MM;Huang X

文献摘要

参考文献

相似文献

帕金森病(PD)的特征在于多巴胺能细胞损失和纹状体体积减小。先前的研究表明,纹状体参与词汇语义知识的获取,这一结构的损伤可能在反应的词汇特性中是明显的。语义流畅性任务的反应,从早期阶段,非痴呆症的PD参与者与右侧(PD-R)或左侧(PD-L)偏侧化症状进行了比较,匹配控制的词汇属性(词频,收购的年龄)和相关的纹状体体积分割T1加权脑MR图像。PD-R参与者产生的语义流畅性反应的年龄低于PD-L和对照参与者(p < 0.05)。在对照组中,获得反应的PD-R年龄与壳核体积呈正相关(p< 0.05),而获得反应的年龄与尾状核体积呈负相关(p< 0.05)。研究结果提供了证据纹状体的作用,在词汇语义访问和词汇访问的定性变化,在选择PD患者。
Parkinson’s disease (PD) is characterized by dopaminergic cell loss and reduced striatal volume. Prior studies have demonstrated striatal involvement in access to lexical-semantic knowledge and damage to this structure may be evident in the lexical properties of responses. Semantic fluency task responses from early stage, non-demented PD participants with right (PD-R) or left (PD-L) lateralizing symptoms were compared to matched controls on lexical properties (word frequency, age of acquisition) and correlated with striatal volumes segmented from T1-weighted brain MR images. PD-R participants produced semantic fluency responses of a lower age of acquisition than PD-L and control participants (p < 0.05). PD-R age of acquisition responses correlated positively with putamen volume (p< 0.05), while age of acquisition of responses correlated negatively with caudate volume in controls (p< 0.05). Findings provide evidence for a role of the striatum in lexical-semantic access and qualitative changes in lexical access in select PD patients.
DOI: 10.1016/s0304-3940(97)00680-0
发表时间: 1997-10-03
影响因子: 2.5
作者:
Abdullaev, YG;Melnichuk, KV
通讯作者: Melnichuk, KV
DOI: 10.1017/s135561770397010x
发表时间: 2003-11-01
影响因子: 2.6
作者:
Crosson, B;Benefield, H;Briggs, RW
通讯作者: Briggs, RW
DOI: 10.1002/mds.20855
发表时间: 2006-07-01
期刊: MOVEMENT DISORDERS
影响因子: 8.6
作者:
Bruck, Anna;Aalto, Sargo;Rinne, Juha O.
通讯作者: Rinne, Juha O.
DOI: 10.1080/13803390500507188
发表时间: 2007-01-01
影响因子: 2.2
作者:
Angwin, Anthony J.;Chenery, Helen J.;Silburn, Peter A.
通讯作者: Silburn, Peter A.
DOI: 10.1076/jcen.20.3.391.810
发表时间: 1998-06-01
影响因子: 2.2
作者:
Crowe, SF
通讯作者: Crowe, SF