Indicators of the acute inflammatory and humoral immune responses in gingival crevicular fluid: relationship to active periodontal disease.

Indicators of the acute inflammatory and humoral immune responses in gingival crevicular fluid: relationship to active periodontal disease.
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龈沟液中急性炎症和体液免疫反应的指标:与活动性牙周病的关系。

DOI:
10.1111/j.1600-0765.1991.tb01653.x
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发表时间:
1991
影响因子:
3.5
通讯作者:
Grbic,JT
Grbic,JT
中科院分区:
医学3区
文献类型:
--
作者:
Lamster,IB;Oshrain,RL;Celenti,RS;Fine,JB;Grbic,JT

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本文讨论了牙周液免疫反应指标及其与牙周动态平衡的关系。多形核白细胞(PMN)被认为是牙周病的关键。动物实验性牙周炎表明,动物的进行性牙周炎与强烈的急性炎症反应的发生和持续有关,而儿童和成人的进行性牙周炎与PMN缺陷有关。膝沟液中胶原酶的主要来源是中性粒细胞。这提示,活跃的PMN反应可能与活动性牙周炎有关。
The article discusses indicators of immune responses in gingival fluid and their relationship to periodontal homeostasis. The polymorphonuclear leukocyte (PMN) is recognized as critical to periodontal disease. Experimental periodontitis in animals indicate that progressive periodontitis in animals is associated with the development and persistence of an intense acute inflammatory response while, that in children and adults indicate the PMN defects. The primary source of collagenase in gengival crevicular fluid is the PMN. It suggets that, an exuberant PMN response can be associated with active periodontitis.
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