Correlation of prefrontal cortical activation with changing vehicle speeds in actual driving: a vector-based functional near-infrared spectroscopy study.
Correlation of prefrontal cortical activation with changing vehicle speeds in actual driving: a vector-based functional near-infrared spectroscopy study.
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DOI：
10.3389/fnhum.2013.00895
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发表时间：
2013
影响因子：
2.9
通讯作者：
Kato T
中科院分区：
文献类型：
--
作者：
Yoshino K;Oka N;Yamamoto K;Takahashi H;Kato T
交通事故在减速时比在加速时更容易发生。然而，人们对大脑活动和车辆加速之间的关系知之甚少，因为很难测量驾驶员在驾驶时的大脑活动。在这项研究中，我们使用基于矢量的功能近红外光谱测量了实际驾驶过程中的大脑活动。受试者在高速公路上行驶时，在白天和晚上分别从100公里/小时减速到50公里/小时（减速任务）和从50公里/小时加速到100公里/小时（提速任务）。我们检查了每个任务中车辆平均加速度与五个血流动力学指标之间的相关性：含氧血红蛋白（ΔoxyHb）、脱氧血红蛋白（ΔdeoxyHb）、脑血容量（ΔCBV）和脑氧交换（ΔCOE）的变化；与其他血红蛋白（Hb）指标的相位角k（度）。ΔoxyHb和ΔCBV反映了脑血流量的变化，而ΔdeoxyHb、ΔCOE和k则与脑氧代谢的变化有关。在所有指数中，大多数与特定大脑部位的相关性都出现在减速而不是加速期间。速度越快，前额叶皮层ΔdeoxyHb、ΔCOE和k的升高幅度越大（r < - 0.5, p < 0.01），尤其是额叶视野，夜间前额叶皮层和顶叶中ΔoxyHb和ΔCBV的降低幅度也越大（r > 0.4, p < 0.01），提示氧代谢与短暂性脑缺血变化有关。我们的研究结果表明，与加速相比，车辆减速需要更多的大脑活动，主要集中在前额叶皮层。从使用指标的角度来看，我们发现同时分析多个血流动力学指标不仅可以检测血流动力学反应的血流成分，还可以检测更多涉及氧代谢的局部额叶激活。
Traffic accidents occur more frequently during deceleration than during acceleration. However, little is known about the relationship between brain activation and vehicle acceleration because it has been difficult to measure the brain activation of drivers while they drive. In this study, we measured brain activation during actual driving using vector-based functional near-infrared spectroscopy. Subjects decelerated from 100 to 50 km/h (speed reduction task) and accelerated from 50 to 100 km/h (speed increase task) while driving on an expressway, in the daytime and at night. We examined correlations between average vehicle acceleration in each task and five hemodynamic indices: changes in oxygenated hemoglobin (ΔoxyHb), deoxygenated hemoglobin (ΔdeoxyHb), cerebral blood volume (ΔCBV), and cerebral oxygen exchange (ΔCOE); and the phase angle k (degrees) derived from the other hemoglobin (Hb) indices. ΔoxyHb and ΔCBV reflect changes in cerebral blood flow, whereas ΔdeoxyHb, ΔCOE, and k are related to variations in cerebral oxygen metabolism. Most of the resulting correlations with specific brain sites, for all the indices, appeared during deceleration rather than during acceleration. Faster deceleration resulted in greater increases in ΔdeoxyHb, ΔCOE, and k in the prefrontal cortex (r < −0.5, p < 0.01), in particular, in the frontal eye field, and at night, it also resulted in greater decreases in ΔoxyHb and ΔCBV in the prefrontal cortex and in the parietal lobe (r > 0.4, p < 0.01), suggesting oxygen metabolism associated with transient ischemic changes. Our results suggest that vehicle deceleration requires more brain activation, focused in the prefrontal cortex, than does acceleration. From the standpoint of the indices used, we found that simultaneous analysis of multiple hemodynamic indices was able to detect not only the blood flow components of hemodynamic responses, but also more localized frontal lobe activation involving oxygen metabolism.
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DOI：
10.1016/j.trf.2004.09.006
发表时间：
2004-07-01
影响因子：
4.1
作者：
Graydon, FX;Young, R;Green, C
通讯作者：
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影响因子：
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发表时间：
1936-01-01
影响因子：
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作者：
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通讯作者：
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