Discrepancy in Fluid and Crystallized Intelligence: An Early Cognitive Marker of Dementia from the LASI-DAD Cohort.
Discrepancy in Fluid and Crystallized Intelligence: An Early Cognitive Marker of Dementia from the LASI-DAD Cohort.
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DOI：
10.1159/000520879
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发表时间：
2022-01
影响因子：
2.3
通讯作者：
Dey, Aparajit Ballav
中科院分区：
文献类型：
--
作者：
Bajpai, Swati;Upadhayay, Ashish Dutt;Banerjee, Joyita;Chakrawarthy, Avinash;Chatterjee, Prashun;Lee, Jinkook;Dey, Aparajit Ballav
认知老化是一个复杂的现象，它包括各种认知技能，大致分为液体和结晶智力。晶体智力（gc）往往会保持，而流体智力（gf）往往会随着年龄的增长而迅速下降。两者与认知能力下降的关系仍然是一个需要进一步研究的猜测问题。本研究的目的是确定变量gc和gf的人口数据的纵向老化研究在印度痴呆症的诊断评估（LASI-DAD）研究，并探讨其与认知功能障碍的发病差异分析对神经心理学测试。这项对LASI-DAD研究数据的分析是在3,223名参与者的样本中进行的。他们进行了广泛的13个认知测试和一个认知的主观测试。标准化评分用于差异分析。以液体能力减去结晶能力来评定认知功能障碍。评分差异>0.99 SD的任何统计学显著性被定义为存在认知下降。以印地语精神状态检查（HMSE）和老年认知功能减退知情人问卷（IQCODE）作为金标准。随着差异评分的增加，每个认知参数评分下降，发现具有统计学意义。在HMSE中（正常= 25.81 ± 3.39;受损= 23.17 ± 3.54; p = <0.001），根据金标准，在人群样本中识别认知障碍的评分下降了2分。类似的趋势在其他神经认知领域也很明显。结晶液智力差异分析在提前预测认知衰退的发生，促进早期干预方面具有很强的潜力。
Cognitive aging is a complex phenomenon, which comprises various cognitive skills, broadly categorized into fluid and crystallized intelligence. Crystallized intelligence (gc) tends to be maintained, as opposed to fluid intelligence (gf), which tends to decline rapidly with age. The association of the two with cognitive decline remains a matter of conjecture requiring further research. The aim of the study was to identify the variables of gc and gf from a population data of Longitudinal Aging Study in India-Diagnostic Assessment of Dementia (LASI-DAD) study and investigate its relationship with the onset of cognitive impairment using discrepancy analysis against neuropsychological tests. This analysis of data from LASI-DAD study was carried out on a sample of 3,223 participants. They were assessed on extensive thirteen cognitive tests and one subjective test of cognition. Standardized score was used for discrepancy analysis. Fluid ability minus crystallized ability was used to assess the cognitive impairment. Any statistical significance with the score difference >0.99 SD was defined as a presence of cognitive decline. Hindi Mental Status Examination (HMSE) and the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) were used as gold standard. With increased discrepancy score, each cognitive parameter score declined which was found to be statistically significant. In HMSE (Normal = 25.81 ± 3.39; Impaired = 23.17 ± 3.54; p = <0.001), there was a drop of 2 point scores in identifying cognitive impairment in the population sample as per the gold standard. A similar trend was evident in other neurocognitive domains as well. Crystallized-fluid intelligence discrepancy analysis has a strong potential in predicting the onset of cognitive decline ahead of time, facilitating early intervention.
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影响因子：
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作者：
Harrington, Karra D.;Dang, Christa;Maruff, Paul
通讯作者：
Maruff, Paul
影响因子：
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DOI：
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发表时间：
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影响因子：
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通讯作者：
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影响因子：
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