Toxoid Vaccination against Bacterial Infection Using Cell Membrane-Coated Nanoparticles.
Toxoid Vaccination against Bacterial Infection Using Cell Membrane-Coated Nanoparticles.
复制标题
DOI：
10.1021/acs.bioconjchem.7b00692
复制
发表时间：
2018-03-21
影响因子：
4.7
通讯作者：
Zhang L
中科院分区：
文献类型：
--
作者：
Angsantikul P;Fang RH;Zhang L
As nanoparticles exhibit unique properties attractive for vaccine development, they have been progressively implemented as antigen delivery platforms and immune potentiators. Recently, cell membrane-coated nanoparticles have provided a novel approach for intercepting and neutralizing bacterial toxins by leveraging their natural affinity to cellular membranes. Such toxin–nanoparticle assemblies, termed nanotoxoids, allow rapid loading of different types of toxins and have been investigated for their ability to effectively confer protection against bacterial infection. This review will cover the current progress in antibacterial vaccine nanoformulations and highlight the nanotoxoid platform as a novel class of nanoparticulate vaccine. We aim to provide insights into the potential of nanotoxoids as a platform that is facile to implement and can be broadly applied to help address the rising threat of super pathogens.
登录
查看更多内容
影响因子：
10.8
作者：
de Groot, Anne Marit;Du, Guangsheng;Sijts, Alice J. A. M.
通讯作者：
Sijts, Alice J. A. M.
纳米颗粒和细胞渗透肽与皮肤的相互作用，以递送透皮药物。
影响因子：
--
作者：
Desai P;Patlolla RR;Singh M
通讯作者：
Singh M
影响因子：
14
作者：
Fang RH;Jiang Y;Fang JC;Zhang L
通讯作者：
Zhang L
DOI：
10.3390/nano6080151
发表时间：
2016-08-19
期刊：
Nanomaterials (Basel, Switzerland)
影响因子：
--
作者：
Calderón-Gonzalez R;Terán-Navarro H;Frande-Cabanes E;Ferrández-Fernández E;Freire J;Penadés S;Marradi M;García I;Gomez-Román J;Yañez-Díaz S;Álvarez-Domínguez C
通讯作者：
Álvarez-Domínguez C
影响因子：
10.8
作者：
Du, Guangsheng;Hathout, Rania M.;Monkare, Juha
通讯作者：
Monkare, Juha