First in vivo traumatic brain injury imaging via magnetic particle imaging.
First in vivo traumatic brain injury imaging via magnetic particle imaging.
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DOI:
10.1088/1361-6560/aa52ad
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发表时间:
2017-05-07
影响因子:
3.5
通讯作者:
Conolly S
中科院分区:
文献类型:
--
作者:
Orendorff R;Peck AJ;Zheng B;Shirazi SN;Matthew Ferguson R;Khandhar AP;Kemp SJ;Goodwill P;Krishnan KM;Brooks GA;Kaufer D;Conolly S
Emergency room visits due to Traumatic Brain Injury (TBI) is common, but classifying the severity of the injury remains an open challenge. Some subjective methods such as the Glasgow Coma Scale attempt to classify traumatic brain injuries, as well as some imaging based modalities such as computed tomography and magnetic resonance imaging. However, to date it is still difficult to detect and monitor mild to moderate injuries. In this report, we demonstrate that the magnetic particle imaging (MPI) modality can be applied to imaging TBI events with excellent contrast. MPI can monitor injected iron nanoparticles over long time scales without signal loss, allowing researchers and clinicians to monitor the change in blood pools as the wound heals.
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DOI:
10.2217/17435889.3.5.703
发表时间:
2008-10
期刊:
Nanomedicine (London, England)
影响因子:
--
作者:
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通讯作者:
Kobayashi H
影响因子:
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作者:
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Labhasetwar, Vinod
影响因子:
14.8
作者:
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通讯作者:
Shohami, Esther
影响因子:
64.8
作者:
Gleich, B;Weizenecker, R
通讯作者:
Weizenecker, R
影响因子:
64.8
作者:
Louveau A;Smirnov I;Keyes TJ;Eccles JD;Rouhani SJ;Peske JD;Derecki NC;Castle D;Mandell JW;Lee KS;Harris TH;Kipnis J
通讯作者:
Kipnis J