The URL1-ROC5-TPL2 transcriptional repressor complex represses the ACL1 gene to modulate leaf rolling in rice.
The URL1-ROC5-TPL2 transcriptional repressor complex represses the ACL1 gene to modulate leaf rolling in rice.
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URL1-ROC5-TPL2 转录抑制复合物抑制 ACL1 基因以调节水稻卷叶
DOI：
10.1093/plphys/kiaa121
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发表时间：
2021-04-23
期刊：
影响因子：
7.4
通讯作者：
Li X
中科院分区：
文献类型：
--
作者：
Fang J;Guo T;Xie Z;Chun Y;Zhao J;Peng L;Zafar SA;Yuan S;Xiao L;Li X
中等的叶子滚动对叶片的直立和紧凑的植物结构有益。 ）由于基于MAP的克隆的数量和大小，显示出叶片的叶子。 （HD-ZIP）IV家族成员大米最外部细胞特异性8（ROC8）。 url1突变体。通过与裸照的OSTPL2相互作用。细胞发育。网络，由ROC5和转录Corepressor TPL2组成的转录表达复合物可抑制ACL1基因的表达，从而调节大米中的牛仔细胞发育和叶片滚动。
转录表达络合物抑制了牛牛细胞发育的阳性调节剂的表达，从而调节牛仔细胞的发育和水稻中的叶片滚动。
Moderate leaf rolling is beneficial for leaf erectness and compact plant architecture. However, our understanding regarding the molecular mechanisms of leaf rolling is still limited. Here, we characterized a semi-dominant rice (Oryza sativa L.) mutant upward rolled leaf 1 (Url1) showing adaxially rolled leaves due to a decrease in the number and size of bulliform cells. Map-based cloning revealed that URL1 encodes the homeodomain-leucine zipper (HD-Zip) IV family member RICE OUTERMOST CELL-SPECIFIC 8 (ROC8). A single-base substitution in one of the two conserved complementary motifs unique to the 3′-untranslated region of this family enhanced URL1 mRNA stability and abundance in the Url1 mutant. URL1 (UPWARD ROLLED LEAF1) contains an ethylene-responsive element binding factor-associated amphiphilic repression motif and functions as a transcriptional repressor via interaction with the TOPLESS co-repressor OsTPL2. Rather than homodimerizing, URL1 heterodimerizes with another HD-ZIP IV member ROC5. URL1 could bind directly to the promoter and suppress the expression of abaxially curled leaf 1 (ACL1), a positive regulator of bulliform cell development. Knockout of OsTPL2 or ROC5 or overexpression of ACL1 in the Url1 mutant partially suppressed the leaf-rolling phenotype. Our results reveal a regulatory network whereby a transcriptional repression complex composed of URL1, ROC5, and the transcriptional corepressor TPL2 suppresses the expression of the ACL1 gene, thus modulating bulliform cell development and leaf rolling in rice. A transcriptional repression complex suppresses the expression of a positive regulator of bulliform cell development, thus modulating bulliform cell development and leaf rolling in rice.
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影响因子：
6.9
作者：
Hao Y;Wang X;Li X;Bassa C;Mila I;Audran C;Maza E;Li Z;Bouzayen M;van der Rest B;Zouine M
通讯作者：
Zouine M
影响因子：
14.8
作者：
Folta, Kevin M.;Kaufman, Lon S.
通讯作者：
Kaufman, Lon S.
影响因子：
7.4
作者：
Kagale, Sateesh;Links, Matthew G.;Rozwadowski, Kevin
通讯作者：
Rozwadowski, Kevin
影响因子：
2.7
作者：
Hibara, Ken-ichiro;Obara, Mari;Nagato, Yasuo
通讯作者：
Nagato, Yasuo
影响因子：
7.2
作者：
Klein-Cosson, Catherine;Chambrier, Pierre;Vernoud, Vanessa
通讯作者：
Vernoud, Vanessa