White matter microstructure is associated with cognitive control in children.
White matter microstructure is associated with cognitive control in children.
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DOI：
10.1016/j.biopsycho.2013.05.008
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发表时间：
2013-09
影响因子：
2.6
通讯作者：
Kramer, Arthur F.
中科院分区：
文献类型：
--
作者：
Chaddock-Heyman, Laura;Erickson, Kirk I.;Voss, Michelle W.;Powers, John P.;Knecht, Anya M.;Pontifex, Matthew B.;Drollette, Eric S.;Moore, R. Davis;Raine, Lauren B.;Scudder, Mark R.;Hillman, Charles H.;Kramer, Arthur F.
认知控制，包括注意力和抑制干扰的能力，对儿童时期的学习和成就很重要。儿童时期与控制有关的白色物质束并不为人所知。我们用扩散张量成像（DTI）检查了61名7 ~ 9岁儿童的白色微结构与认知控制之间的关系。该技术能够基于扩散特性对白色物质的微观结构特性进行体内表征。这些特性包括分数各向异性、平均扩散率、轴向扩散率和径向扩散率，这些测量被认为反映了白色物质完整性的特定生物学特性。我们的研究结果表明，在认知控制任务的不一致（>><>>，<<><<）和中性（-->--，--<--）试验中，对辐射冠、上级纵束、丘脑后辐射和大脑脚中白色物质完整性估计较高的儿童更准确。重要的是，任务期间的干扰更少（即，不一致和中性差异评分）与丘脑后辐射区和大脑脚中更大的白色物质显微结构相关。额顶叶-纹状体-运动回路中的纤维束似乎在儿童的认知控制中发挥作用。
Cognitive control, which involves the ability to pay attention and suppress interference, is important for learning and achievement during childhood. The white matter tracts related to control during childhood are not well known. We examined the relationship between white matter microstructure and cognitive control in 61 children aged 7 to 9 years using diffusion tensor imaging (DTI). This technique enables an in vivo characterization of microstructural properties of white matter based on properties of diffusion. Such properties include fractional anisotropy, mean diffusivity, axial diffusivity, and radial diffusivity, measures thought to reflect specific biological properties of white matter integrity. Our results suggest that children with higher estimates of white matter integrity in the corona radiata, superior longitudinal fasciculus, posterior thalamic radiation, and cerebral peduncle, were more accurate during incongruent (>><>>, <<><<) and neutral (-->--, --<--) trials of a task of cognitive control. Importantly, less interference during the task (i.e., incongruent and neutral difference scores) was associated with greater white matter microstructure in the posterior thalamic radiation and cerebral peduncle. Fiber tracts in a frontal-parietal-striatal-motor circuit seem to play a role in cognitive control in children.
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影响因子：
2.6
作者：
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通讯作者：
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