Relationships among blood pressure, triglycerides and verbal learning in African Americans.

Relationships among blood pressure, triglycerides and verbal learning in African Americans.
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非洲裔美国人的血压,甘油三酸酯和言语学习之间的关系。

DOI:
10.1016/s0027-9684(15)31474-7
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发表时间:
2008-10
影响因子:
3.3
通讯作者:
Campbell, Alfonso L., Jr.
Campbell, Alfonso L., Jr.
中科院分区:
医学4区
文献类型:
--
作者:
Sims, Regina C.;Madhere, Serge;Gordon, Shalanda;Clark, Elijah, Jr.;Abayomi, Kobi A.;Callender, Clive O.;Campbell, Alfonso L., Jr.

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心血管疾病 (CVD) 风险较高的个体在各个认知领域表现出较差的认知功能。这一发现在老年人中尤其普遍;然而,很少有研究考察年轻人或非裔美国人之间的这些关系。目的是检查 2 个心血管危险因素、血压升高和甘油三酯升高以及非裔美国人社区样本中的语言学习之间的关系。对 121 名非裔美国成年人进行了血压和甘油三酯测量,并与加州语言学习测试 II (CVLT-II) 3 个领域的表现进行比较。血压与 CVLT-II 表现无关。甘油三酯水平与 CVLT-II 表现呈负相关。较高的甘油三酯水平与较差的即时、短延迟和长延迟回忆相关。与涉及老年参与者的研究一致,当前的调查表明,在非老年非裔美国人样本中,甘油三酯水平可能与认知功能有关。由于血管相关认知障碍的早期发现和干预可能具有有益作用,因此未来的研究应包括年轻人,以强调心血管风险对认知的影响。
Individuals at greater risk for cardiovascular disease (CVD) display poorer cognitive functioning across various cognitive domains. This finding is particularly prevalent among older adults; however, few studies examine these relationships among younger adults or among African Americans. The objective was to examine the relationships among 2 cardiovascular risk factors, elevated blood pressure and elevated triglycerides, and verbal learning in a community-based sample of African Americans. Measurements of blood pressure and triglycerides were obtained in 121 African-American adults and compared to performance on 3 domains of the California Verbal Learning Test-II (CVLT-II). Blood pressure was not related to CVLT-II performance. Triglyceride levels were inversely related to CVLT-II performance. Higher triglyceride levels were associated with poorer immediate, short delay and long delay recall. Consistent with studies involving older participants, the current investigation shows that in a nonelderly sample of African Americans, triglyceride levels may be related to cognitive functioning. Because early detection and intervention of vascular-related cognitive impairment may have a salutary effect, future studies should include younger adults to highlight the impact of cardiovascular risk on cognition.
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发表时间: 2006-02-07
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影响因子: 37.8
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期刊: HYPERTENSION
影响因子: 8.3
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