Healthy Adolescent Performance With Standardized Scoring Tables for the MATRICS Consensus Cognitive Battery: A Multisite Study.
Healthy Adolescent Performance With Standardized Scoring Tables for the MATRICS Consensus Cognitive Battery: A Multisite Study.
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DOI：
10.1093/schbul/sby131
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发表时间：
2019-06-18
影响因子：
6.6
通讯作者：
Agartz I
中科院分区：
文献类型：
--
作者：
Smelror RE;Jørgensen KN;Lonning V;Kelleher I;Cannon M;DeRosse P;Malhotra AK;Karlsgodt KH;Andreassen OA;Lundberg M;Edbom T;Cleland N;Ueland T;Myhre AM;Rund BR;Agartz I
本研究的目的是为健康青少年的测试表现制定标准化分数和评分表，用于改善精神分裂症认知的测量和治疗研究 (MATRICS) 共识认知电池 (MCCB)，每年按性别划分 11 至 19 岁，并提供 T 分数和百分位数排名。这项多中心研究共纳入了来自爱尔兰、挪威、瑞典和美国 7 个队列的 502 名健康参与者（年龄 11-19 岁）。 MCCB 测试（社会认知子测试除外）的回归预测平均值是使用 MCCB 测试分数作为结果变量，年龄、年龄 2、性别、年龄 × 性别作为预测变量来计算的。将每个年龄和性别组合的回归预测平均值与整个队列的残差相加，得出该组的预期分布。使用以年龄和年龄2作为预测变量的回归模型来检查年龄效应。使用学生 t 检验检查性别差异。除修订后的简短视觉空间记忆测试（BVMT-R；视觉学习测量）外，所有测试都发现了显着的积极年龄影响。女性在 BACS 符号编码（处理速度的衡量标准）和 BVMT-R 上的表现明显优于男性，而男性在 NAB 迷宫（推理和问题解决的衡量标准）上的表现明显优于女性。根据回归预测的分数分布，为每个测试和领域创建了 19 个标准化评分表。根据这项研究的结果，我们为 MCCB 开发了一个可访问的健康青少年测试表现标准化数据集。
The aim of this study was to develop standardized scores and scoring tables for test performance in healthy adolescents for the Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) Consensus Cognitive Battery (MCCB) for each year from 11 to 19 years of age, by sex, with T scores and percentile ranks. A total of 502 healthy participants (aged 11–19 years) from 7 cohorts from Ireland, Norway, Sweden, and United States, were included in this multisite study. Regression-predicted means for the MCCB tests, except the social cognition subtest, were calculated using the MCCB test scores as outcome variables and age, age2, sex, age × sex as predictors. The regression-predicted means for each combination of age and sex were added with the residuals from the entire cohort to yield the expected distribution of that group. Age effects were examined using regression models with age and age2 as predictors. Sex differences were examined using Student’s t-tests. Significant positive age effects were found for all tests, except for the Brief Visuospatial Memory Test, revised (BVMT-R; measure of visual learning). Females performed significantly better than males on BACS Symbol coding (measure of speed of processing) and BVMT-R, while males performed significantly better than females on NAB Mazes (measure of reasoning and problem solving). Based on the regression-predicted distributions of scores, 19 standardized scoring tables for each test and domain were created. With the results from this study, we have developed an accessible standardized data set of healthy adolescent test performance for the MCCB.
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影响因子：
4.5
作者：
Nitzburg, George C.;DeRosse, Pamela;Malhotra, Anil K.
通讯作者：
Malhotra, Anil K.
影响因子：
6.6
作者：
Holmen, Aina;Juuhl-Langseth, Monica;Rund, Bjrn Rishovd
通讯作者：
Rund, Bjrn Rishovd
影响因子：
11.3
作者：
CORNBLATT, BA;RISCH, NJ;ERLENMEYERKIMLING, L
通讯作者：
ERLENMEYERKIMLING, L
影响因子：
1.9
作者：
Baillargeon, Annie;Lassonde, Maryse;Ellemberg, Dave
通讯作者：
Ellemberg, Dave
影响因子：
17.7
作者：
Kern, Robert S.;Nuechterlein, Keith H.;Marder, Stephen R.
通讯作者：
Marder, Stephen R.