The role of extracellular vesicles in Plasmodium and other protozoan parasites.
The role of extracellular vesicles in Plasmodium and other protozoan parasites.
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DOI:
10.1111/cmi.12259
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发表时间:
2014-03
影响因子:
3.4
通讯作者:
Marti M
中科院分区:
文献类型:
--
作者:
Mantel PY;Marti M
Protozoan parasites and other microorganisms use various pathways to communicate within their own populations and to manipulate their outside environments, with the ultimate goal of balancing the rate of growth and transmission. In higher eukaryotes, including humans, circulating extracellular vesicles are increasingly recognized as key mediators of physiological and pathological processes. Recent evidence suggests that protozoan parasites, including those responsible for major human diseases such as malaria and Chagas disease, use similar machinery. Indeed, intracellular and extracellular protozoan parasites secrete extracellular vesicles to promote growth and induce transmission, to evade the host immune system, and to manipulate the microenvironment. In this review we will discuss the general pathways of extracellular vesicle biogenesis and their functions in protozoan infections.
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影响因子:
3
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DOI:
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发表时间:
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期刊:
The Journal of cell biology
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DOI:
10.1083/jcb.200508014
发表时间:
2006-03-13
期刊:
The Journal of cell biology
影响因子:
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