Development. Esophageal stem cells, where art thou?

Development. Esophageal stem cells, where art thou?
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发展。食管干细胞,您在哪里?

DOI:
10.1126/science.1227506
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发表时间:
2012-08-31
期刊:
Science (New York, N.Y.)
影响因子:
--
通讯作者:
Kushner JA
Kushner JA
中科院分区:
其他
文献类型:
--
作者:
Kushner JA

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食道腔内衬鳞状复层上皮。在Doupé等人的模型中(基于小鼠食管上皮),基底层上方存在单一的上皮祖细胞群(黄色)。在基础条件下,上皮由这些细胞维持,这些细胞分裂并产生更多的祖细胞或分化成复层上皮的层
The lumen of the esophagus is lined with a squamous stratified epithelium. In the model of Doupé et al. (based on the mouse esophageal epithelium), a single population of epithelial progenitor cells (yellow) is present above the basal lamina. The epithelium is maintained, under basal conditions, by these cells, which divide and produce both more progenitor cells or differentiate into the layers of the stratified epithelium
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