Effect of the chest wall on breast lesion reconstruction.

Effect of the chest wall on breast lesion reconstruction.
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DOI:
10.1117/1.3160548
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发表时间:
2009-07
影响因子:
3.5
通讯作者:
Zhu Q
Zhu Q
中科院分区:
医学3区
文献类型:
--
作者:
Ardeshirpour Y;Huang M;Zhu Q

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乳房组织下面的胸壁会影响用反射几何学测量的近红外(NIR)漫射波。在共同配准超声的帮助下,可以确定胸壁的深度和倾斜角,并将其用于将乳房建模为双层介质。有限元方法适用于模拟复杂的边界条件,适用于模拟乳房组织和胸壁。估计了这两层膜的体吸收系数和折合散射系数的四个参数,并将其用于成像重建。利用两层模型,我们系统地研究了胸壁对乳房病变重建的影响。结果表明,胸壁深度、倾斜角度以及两层病变与参考点的光学性质差异对病变重建的影响不同。我们的分析将对使用反射几何学进行乳房成像的研究人员具有价值和参考价值。该分析还可以为成像操作员提供指导,以最大限度地减少图像伪影并产生最佳重建结果。
The chest wall underneath the breast tissue affects near-infrared (NIR) diffusive waves measured with reflection geometry. With the assistance of a co-registered ultrasound, the depth and the tilting angle of the chest wall can be determined and are used to model the breast as a two-layer medium. Finite element method (FEM) is suitable for modeling complex boundary conditions and is adapted to model the breast tissue and chest wall. Four parameters of bulk absorption and reduced scattering coefficients of these two layers are estimated and used for imaging reconstruction. Using a two-layer model, we have systematically investigated the effect of the chest wall on breast lesion reconstruction. Results have shown that chest-wall depth, titling angle, and difference between optical properties of two layers of lesion and reference sites affect the lesion reconstruction differently. Our analysis will be valuable and informative to researchers who are using reflectance geometry for breast imaging. The analysis can also provide guidelines for imaging operators to minimize image artifacts and to produce the best reconstruction results.
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