The maximum standardized FDG uptake on PET-CT in patients with non-small cell lung cancer.
The maximum standardized FDG uptake on PET-CT in patients with non-small cell lung cancer.
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DOI：
10.1186/2049-6958-8-69
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发表时间：
2013-10-22
影响因子：
2.3
通讯作者：
Yüksel M
中科院分区：
文献类型：
--
作者：
Ozgül MA;Kirkil G;Seyhan EC;Cetinkaya E;Ozgül G;Yüksel M
非小细胞肺癌（NSCLC）约占新诊断肺癌的80%。本研究探讨了计算机断层扫描综合正电子发射断层扫描中18f -氟脱氧葡萄糖摄取与非小细胞肺癌患者肿瘤大小、淋巴结转移和远处转移的相关性。回顾性分析151例非小细胞肺癌患者的临床资料，其中男139例，女12例，平均年龄59.60岁。腺癌41例；鳞状细胞癌45例；非小细胞肺癌65例。按肿瘤大小分（1组≤3cm， 2组> 3≤5cm， 3组> 5 cm）， 1组和2组最大标准化摄取值（SUVmax）明显低于3组（p = 0.006）。考虑到所有病例，肿瘤SUVmax与年龄、性别或组织病理类型无关。24例经病理证实有淋巴结转移：其中24%为腺癌，6%为鳞状细胞癌，16%为非小细胞肺癌。淋巴结受累和远处转移均与肿瘤SUVmax无关，但淋巴结大小与淋巴结SUVmax呈正相关（r = 0.775; p < 0.001）。SUVmax与肿瘤大小显著相关，但与远处转移或淋巴结累及无关。因此，正电子发射断层扫描的SUVmax不能预测转移的存在。
Non-small cell lung cancer (NSCLC) accounts for approximately 80% of new diagnoses of pulmonary carcinoma. This study investigated the correlation between 18 F-fluorodeoxyglucose uptake in computerized tomography integrated positron emission tomography and tumor size, lymph node metastasis, and distant metastasis in patients with NSCLC. The records of 151 NSCLC patients (139 male, 12 female; mean age 59.60 years) were evaluated retrospectively. Forty-one cases were adenocarcinomas; 45 squamous cell carcinomas; and 65 unspecified NSCLC. When the cases were categorized according to tumor size (group 1, ≤ 3 cm; group 2, > 3 and ≤ 5 cm; group 3, > 5 cm), the maximum standardized uptake value (SUVmax) was significantly lower in groups 1 and 2 compared with group 3 (p = 0.006 for each). Considering all cases, tumor SUVmax was not correlated with age, gender, or histopathological type. Lymph node metastases were pathologically proven in 24 cases: 24% of these were adenocarcinomas, 6% squamous cell carcinomas, and 16% unspecified NSCLC. Neither lymph node involvement nor distant metastases were correlated with tumor SUVmax, although lymph node size was positively correlated with lymph node SUVmax (r = 0.775; p < 0.001). SUVmax was significantly associated with tumor size, but not with distant metastases or lymph node involvement. Therefore, SUVmax on positron emission tomography is not predictive of the presence of metastases.
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影响因子：
4.8
作者：
Chang JM;Lee HJ;Goo JM;Lee HY;Lee JJ;Chung JK;Im JG
通讯作者：
Im JG
影响因子：
19.7
作者：
Kim, Byung-Tae;Lee, Kyung Soo;Kim, Seonwoo
通讯作者：
Kim, Seonwoo
DOI：
10.1007/s00259-005-1953-2
发表时间：
2006-03-01
影响因子：
9.1
作者：
Eschmann, SM;Friedel, G;Bares, R
通讯作者：
Bares, R
影响因子：
1.5
作者：
Jeong, HJ;Min, JJ;Shim, YS
通讯作者：
Shim, YS
影响因子：
2.6
作者：
Nambu, Atsushi;Kato, Satoshi;Araki, Tsutomu
通讯作者：
Araki, Tsutomu