Towards a systems-level understanding of development in the marine annelid Platynereis dumerilii.
Towards a systems-level understanding of development in the marine annelid Platynereis dumerilii.
复制标题
对海洋环节动物 Platynereis dumerilii 发育的系统级理解
DOI:
10.1016/j.gde.2016.07.005
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发表时间:
2016
影响因子:
4
通讯作者:
Jékely G
中科院分区:
文献类型:
--
作者:
Williams EA;Jékely G
Platynereis dumeriliiis a segmented marine worm from the phylum Annelida, a member of the Lophotrochozoans.Platynereisis easily maintained in the lab and exhibits a highly stereotypic development through spiral cleavage with a small, transparent, free-swimming larva highly suitable for microscopy studies. A protocol for embryo microinjection inPlatynereishas enabled several genetic tools to be developed, paving the way for functional studies. RecentPlatynereisstudies have provided insights into the function of several signaling pathways in development.Platynereishas also proven a useful model system for comparative evolutionary developmental studies, allowing the formation of new hypotheses on the evolution of neuroendocrine signaling, body patterning, and organ development. Combining existing large datasets of spatial gene expression mapping, cell lineage mapping, and neuronal circuits with functional analyses of developmental genes represents a promising approach for future studies aiming at a systems-level understanding of development inPlatynereis.
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影响因子:
3.7
作者:
Ramanathan N;Simakov O;Merten CA;Arendt D
通讯作者:
Arendt D
影响因子:
3
作者:
Albina Asadulina;Markus Conzelmann;Elizabeth A. Williams;Aurora Panzera;G. Jékely
通讯作者:
G. Jékely
影响因子:
7.7
作者:
Randel N;Shahidi R;Verasztó C;Bezares-Calderón LA;Schmidt S;Jékely G
通讯作者:
Jékely G
影响因子:
3.7
作者:
Pfeifer K;Schaub C;Domsch K;Dorresteijn A;Wolfstetter G
通讯作者:
Wolfstetter G
影响因子:
10.7
作者:
Struck;Wey-Fabrizius;Golombeck;Hering;Weigert;Bleidorn;Klebow;Iakovenko;Hausdorf;Petersen;Herlyn;Hankeln
通讯作者:
Hankeln