Neural correlates of effort-based valuation with prospective choices.
Neural correlates of effort-based valuation with prospective choices.
复制标题
DOI：
10.1016/j.neuroimage.2018.10.051
复制
发表时间：
2019-01-15
期刊：
影响因子：
5.7
通讯作者：
Schonberg T
中科院分区：
文献类型：
--
作者：
Aridan N;Malecek NJ;Poldrack RA;Schonberg T
如何将努力融入基于价值的决策？动物模型和人类神经影像学研究主要将前扣带皮层（ACC）和腹侧纹状体（VS）与评估努力的整合联系起来。其他研究证明了这些区域在激发努力需求方面的作用，因此很难将与预期和主观评价相关的神经活动与实际表现分开。在这里，我们研究了与绩效分离的努力评估的神经基础。我们用功能磁共振成像扫描了四十名参与者，他们被要求接受或拒绝金钱赌博，这些赌博可以通过未来表现熟悉的握力努力挑战或固定风险前景来解决。参与者接受预期赌博的意愿反映了体力努力和风险对价值的折扣。对侧初级感觉皮层和腹内侧前额叶皮层（vmPFC）中的选择锁定神经激活跟踪参与者面临的预期努力的大小，与选择时间和金钱风险无关。人们发现，通过努力打折的主观价值估计是通过风险和延迟下评估所共有的区域网络的激活来跟踪的，这些区域包括 vmPFC、VS 和感觉运动皮层。总之，我们的研究结果显示了潜在努力和实际努力表现背后的不同神经机制。
How is effort integrated in value-based decision-making? Animal models and human neuroimaging studies primarily linked the anterior cingulate cortex (ACC) and ventral striatum (VS) to the integration of effort in valuation. Other studies demonstrated the role of these regions in invigoration to effort demands, thus it is hard to separate the neural activity linked to anticipation and subjective valuation from actual performance. Here, we studied the neural basis of effort valuation separated from performance. We scanned forty participants with fMRI, while they were asked to accept or reject monetary gambles that could be resolved with future performance of a familiar grip force effort challenge or a fixed risk prospect. Participants’ willingness to accept prospective gambles reflected discounting of values by physical effort and risk. Choice-locked neural activation in contralateral primary sensory cortex and ventromedial prefrontal cortex (vmPFC) tracked the magnitude of prospective effort the participants faced, independent of choice time and monetary stakes. Estimates of subjective value discounted by effort were found to be tracked by the activation of a network of regions common to valuation under risk and delay, including vmPFC, VS and sensorimotor cortex. Together, our findings show separate neural mechanisms underlying prospective effort and actual effort performance.
登录
查看更多内容
影响因子：
5.7
作者：
Bartra, Oscar;McGuire, Joseph T.;Kable, Joseph W.
通讯作者：
Kable, Joseph W.
影响因子：
10.6
作者：
Day, Jeremy J.;Jones, Joshua L.;Wightman, R. Mark;Carelli, Regina M.
通讯作者：
Carelli, Regina M.
影响因子：
5.7
作者：
Deichmann, R;Gottfried, JA;Turner, R
通讯作者：
Turner, R
影响因子：
5.7
作者：
Dale, AM;Fischl, B;Sereno, MI
通讯作者：
Sereno, MI
DOI：
10.1523/jneurosci.4515-08.2009
发表时间：
2009-04-08
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
--
作者：
Croxson PL;Walton ME;O'Reilly JX;Behrens TE;Rushworth MF
通讯作者：
Rushworth MF