Bacteriological, Clinical and Virulence Aspects of Aeromonas-associated Diseases in Humans.
Bacteriological, Clinical and Virulence Aspects of Aeromonas-associated Diseases in Humans.
复制标题
人类与空气负体相关疾病的细菌学，临床和毒力方面。
DOI：
10.21307/pjm-2018-020
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发表时间：
2018-06-30
影响因子：
2.1
通讯作者：
Bhattacharjee S
中科院分区：
文献类型：
--
作者：
Bhowmick UD;Bhattacharjee S
气单胞菌已从各种环境来源如污染水和饮用水以及冷血和温血动物的组织和体液中分离出来。气单胞菌是一种表型和基因型异质性细菌，除了经典的生化特征外，还可以通过核糖体分型和/或分析gyrB基因序列来成功鉴定。已知气单胞菌引起水生生物的怀疑症、胃肠炎和肠外疾病，如人类的怀疑症、皮肤、眼睛、伤口和呼吸道感染。已经从这群细菌中鉴定和分离出了几个毒力和抗生素抗性基因，如果这些基因存在于它们的移动的遗传元件中，则可能水平转移到其他对社会构成威胁的幼稚环境细菌中。抗生素的广泛和不分青红皂白的使用导致了许多耐药细菌的产生。多重耐药基因，如NDM 1，已被确定在这组细菌是严重的健康问题。因此，了解抗生素耐药性是如何发展和传播的，以便采取预防措施是很重要的。寻找和定位气单胞菌的毒力基因，对防治气单胞菌引起的疾病也是十分必要的。本文综述了气单胞菌群的细菌学、环境、临床和毒力方面的知识，以及人类和其他动物的相关疾病。
Aeromonads have been isolated from varied environmental sources such as polluted and drinking water, as well as from tissues and body fluids of cold and warm-blooded animals. A phenotypically and genotypically heterogenous bacteria, aeromonads can be successfully identified by ribotyping and/or by analysing gyrB gene sequence, apart from classical biochemical characterization. Aeromonads are known to cause scepticemia in aquatic organisms, gastroenteritis and extraintestinal diseases such as scepticemia, skin, eye, wound and respiratory tract infections in humans. Several virulence and antibiotic resistance genes have been identified and isolated from this group, which if present in their mobile genetic elements, may be horizontally transferred to other naive environmental bacteria posing threat to the society. The extensive and indiscriminate use of antibiotics has given rise to many resistant varieties of bacteria. Multidrug resistance genes, such as NDM1, have been identified in this group of bacteria which is of serious health concern. Therefore, it is important to understand how antibiotic resistance develops and spreads in order to undertake preventive measures. It is also necessary to search and map putative virulence genes of Aeromonas for fighting the diseases caused by them. This review encompasses current knowledge of bacteriological, environmental, clinical and virulence aspects of the Aeromonas group and related diseases in humans and other animals of human concern.
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影响因子：
14.2
作者：
Alperi, A.;Figueras, M. J.
通讯作者：
Figueras, M. J.
DOI：
10.1099/ijs.0.011643-0
发表时间：
2010-01-01
影响因子：
2.8
作者：
Alperi, Anabel;Martinez-Murcia, Antonio J.;Figueras, Maria J.
通讯作者：
Figueras, Maria J.
DOI：
10.1099/ijs.0.040162-0
发表时间：
2013-06-01
影响因子：
2.8
作者：
Aravena-Roman, Max;Beaz-Hidalgo, Roxana;Jose Figueras, Maria
通讯作者：
Jose Figueras, Maria
影响因子：
4.4
作者：
ANGUITA, J;APARICIO, LBR;NAHARRO, G
通讯作者：
NAHARRO, G
影响因子：
2.8
作者：
CHOPRA, AK;HOUSTON, CW;JIN, GF
通讯作者：
JIN, GF