cAMP and mitochondria.
cAMP and mitochondria.
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DOI:
10.1152/physiol.00004.2013
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发表时间:
2013-05
期刊:
影响因子:
--
通讯作者:
Manfredi G
中科院分区:
文献类型:
--
作者:
Valsecchi F;Ramos-Espiritu LS;Buck J;Levin LR;Manfredi G
Phosphorylation of mitochondrial proteins has emerged as a major regulatory mechanism for metabolic adaptation. cAMP signaling and PKA phosphorylation of mitochondrial proteins has just started to be investigated, and the presence of cAMP generating enzymes and PKA inside mitochondria is still controversial. Here, we discuss the role of cAMP in regulating mitochondrial bioenergetics through protein phosphorylation and the evidence for soluble adenylyl cyclase as the source of cAMP inside mitochondria.
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DOI:
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发表时间:
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期刊:
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