Delta hepatitis: molecular biology and clinical and epidemiological features

Delta hepatitis: molecular biology and clinical and epidemiological features
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丁型肝炎:分子生物学以及临床和流行病学特征

DOI:
--
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发表时间:
1993
影响因子:
36.8
通讯作者:
S. C. Hadler
S. C. Hadler
中科院分区:
医学1区
文献类型:
--
作者:
L. Polish;M. Gallagher;H. Fields;S. C. Hadler

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Hepatitis delta virus, discovered in 1977, requires the help of hepatitis B virus to replicate in hepatocytes and is an important cause of acute, fulminant, and chronic liver disease in many regions of the world. Because of the helper function of hepatitis delta virus, infection with it occurs either as a coinfection with hepatitis B or as a superinfection of a carrier of hepatitis B surface antigen. Although the mechanisms of transmission are similar to those of hepatitis B virus, the patterns of transmission of delta virus vary widely around the world. In regions of the world in which hepatitis delta virus infection is not endemic, the disease is confined to groups at high risk of acquiring hepatitis B infection and high-risk hepatitis B carriers. Because of the propensity of this viral infection to cause fulminant as well as chronic liver disease, continued incursion of hepatitis delta virus into areas of the world where persistent hepatitis B infection is endemic will have serious implications. Prevention depends on the widespread use of hepatitis B vaccine. This review focuses on the molecular biology and the clinical and epidemiologic features of this important viral infection.
实验性重复感染乙型肝炎病毒携带者黑猩猩的慢性丁型肝炎病毒 (HDV) 感染。
DOI: 10.1093/infdis/158.1.151
发表时间: 1988
期刊: The Journal of infectious diseases
影响因子: --
作者:
Negro,F;Bergmann,KF;Baroudy,BM;Satterfield,WC;Popper,H;Purcell,RH;Gerin,JL
通讯作者: Gerin,JL
丁型肝炎抗原的异质性。
DOI: 10.1016/0042-6822(90)90415-n
发表时间: 1990
期刊: Virology
影响因子: 3.7
作者:
Xia,YP;Chang,MF;Wei,D;Govindarajan,S;Lai,MM
通讯作者: Lai,MM
丁型肝炎病毒的结构和复制。
DOI: 10.1146/annurev.mi.46.100192.001345
发表时间: 1992
影响因子: 10.5
作者:
Taylor,JM
通讯作者: Taylor,JM
患有和未患有艾滋病的肠外吸毒者中丁型肝炎标志物的流行率对比。
DOI: 10.1093/infdis/162.2.538
发表时间: 1990
期刊: The Journal of infectious diseases
影响因子: --
作者:
Kreek,MJ;DesJarlais,DC;Trepo,CL;Novick,DM;Abdul-Quader,A;Raghunath,J
通讯作者: Raghunath,J
丁型肝炎病毒 RNA 的可逆切割和连接。
DOI: 10.1126/science.2492677
发表时间: 1989
期刊: Science (New York, N.Y.)
影响因子: --
作者:
Wu,HN;Lai,MM
通讯作者: Lai,MM