Reasons for being unsure or unwilling regarding intention to take COVID-19 vaccine among Japanese people: A large cross-sectional national survey.
Reasons for being unsure or unwilling regarding intention to take COVID-19 vaccine among Japanese people: A large cross-sectional national survey.
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DOI：
10.1016/j.lanwpc.2021.100223
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发表时间：
2021-09
期刊：
影响因子：
--
通讯作者：
Miyata H
中科院分区：
文献类型：
--
作者：
Nomura S;Eguchi A;Yoneoka D;Kawashima T;Tanoue Y;Murakami M;Sakamoto H;Maruyama-Sakurai K;Gilmour S;Shi S;Kunishima H;Kaneko S;Adachi M;Shimada K;Yamamoto Y;Miyata H
识别和理解不确定或不愿意接种冠状病毒病（COVID-19）疫苗的原因可能有助于为未来旨在提高疫苗接种覆盖率的公共卫生信息提供信息。我们分析了日本人在COVID-19疫苗接种决策方面的各种心理倾向。2021年2月底，对30053名20岁以上的日本成年人进行了具有全国代表性的横断面网络调查。除了关于个人接种COVID-19疫苗的意愿的问题外，受访者还被问及他们的社会人口、健康相关和心理特征，以及关于COVID-19的信息来源和他们的信任程度。此外，那些回答“不确定”或“不”是否打算接种COVID-19疫苗的人被问及原因。使用具有稀疏组Lasso（最小绝对收缩和选择算子）罚分的多项逻辑回归计算与意图相关的因素的校正比值比（不确定/否vs是）。对于接种COVID-19疫苗的意向，回答“不确定”或“否”的受访者比例分别为32. 9%和11. 0%。在调整协变量后，COVID-19的感知风险、COVID-19疫苗的感知风险、COVID-19疫苗的感知益处、对科学家和公共当局的信任以及医务工作者应该接种疫苗的信念与疫苗接种意愿显著相关。关于COVID-19的几个信息来源也与疫苗接种意愿显著相关，包括医生、护士和电视、医疗信息网站，不确定或不愿意的几率较低，互联网新闻网站、YouTube、家庭成员以及科学家和研究人员的几率较高。对电视作为COVID-19信息来源的信任程度越高，回答“不确定”的几率就越高（比值比1.11，95%置信区间1.01-1.21）。我们还发现，许多受访者对COVID-19疫苗的副作用和安全性表示担忧，这是不确定或不愿意接种的主要原因。为了决定是否接种疫苗，许多受访者要求获得更多信息，包括疫苗与其个人健康状况之间的相容性、其他人是否接种过疫苗、疫苗对变异的有效性以及医生的建议。我们的研究结果表明，基于那些不确定或不愿意接种COVID-19疫苗的人的社会人口统计学和心理特征的公共卫生信息可能有助于增加这一人群的疫苗接种。目前的工作得到了日本厚生劳动省（H29-Gantaisaku-ippan-009）的部分资助。
Identifying and understanding reasons for being unsure or unwilling regarding intention to be vaccinated against coronavirus disease (COVID-19) may help to inform future public health messages aimed at increasing vaccination coverage. We analyzed a broad array of individual's psychological dispositions with regard to decision-making about COVID-19 vaccination in Japan. A nationally representative cross-sectional web survey was conducted with 30053 Japanese adults aged 20 years or older at the end of February 2021. In addition to the question on the individual's intention to be vaccinated against COVID-19, respondents were asked about their sociodemographic, health-related, and psychological characteristics as well as information sources about COVID-19 and their levels of trust. Also, those who responded ‘not sure’ or ‘no’ regarding intention to take COVID-19 vaccine were asked why. Multinomial logistic regression with sparse group Lasso (Least Absolute Shrinkage and Selection Operator) penalty was used to compute adjusted odds ratios for factors associated with the intention (not sure/no versus yes). The percentages of respondents who answered ‘not sure’ or ‘no’ regarding intention to be vaccinated against COVID-19 vaccine were 32.9% and 11.0%, respectively. After adjusting for covariates, the perceived risks of COVID-19, perceived risk of a COVID-19 vaccine, perceived benefits of a COVID-19 vaccine, trust in scientists and public authorities, and the belief that healthcare workers should be vaccinated were significantly associated with vaccination intention. Several sources of information about COVID-19 were also significantly associated with vaccination intention, including physicians, nurses, and television, medical information sites with lower odds of being unsure or unwilling, and internet news sites, YouTube, family members, and scientists and researchers with higher odds. The higher the level of trust in television as a source of COVID-19 information, the higher the odds of responding ‘not sure’ (odds ratio 1.11, 95% confidence interval 1.01–1.21). We also demonstrated that many respondents presented concerns about the side effects and safety of a COVID-19 vaccine as a major reason for being unsure or unwilling. To decide whether or not to get the vaccine, many respondents requested more information about the compatibilities between the vaccine and their personal health conditions, whether other people had been vaccinated, the effectiveness of vaccines against variants, and doctors’ recommendations. Our findings suggest that public health messaging based on the sociodemographic and psychological characteristics of those who are unsure or unwilling regarding intention to be vaccinated against COVID-19 vaccine may help to increase vaccine uptake amongst this population. The present work was supported in part by a grant from the Ministry of Health, Labour and Welfare of Japan (H29-Gantaisaku-ippan-009).
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