Dynamic changes in metabolic health status in Chinese adults: Multiple population-based surveys in Shanghai, China.
Dynamic changes in metabolic health status in Chinese adults: Multiple population-based surveys in Shanghai, China.
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中国成年人代谢健康状况的动态变化：中国上海的多项人群调查
DOI：
10.1111/jdi.13556
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发表时间：
2021-10
影响因子：
3.2
通讯作者：
Shi Y
中科院分区：
文献类型：
--
作者：
Yang Y;Li Y;Pei J;Cheng M;Xu W;Shi Y
代谢综合征（MS）在全球范围内不断增加。然而，MS组分的长期变化仍不清楚。本研究旨在探讨中国成年人代谢健康状况的动态变化。2002-2003年（n = 12，302）、2009年（n = 7，400）和2017年（n = 19，023），在上海35-74岁的中国人中使用多阶段分层抽样进行了三项基于人群的调查。根据亚裔美国人成人治疗组III标准定义MS。使用广义估计方程和Cochran-Armitage趋势检验评估多年来的患病率趋势。在此期间，中国成年人的MS患病率翻了一番（趋势P < 0.001）。最大的增长发生在年轻人身上。在MS组分中，所有受试者中高腰围（HWC）、高血糖（HBG）和高血压（HBP）的患病率增加，而男性中高甘油三酯（HTG）和低高密度脂蛋白胆固醇（LHC）的患病率增加，但女性中降低。HBP的增加对MS升高的贡献最大，其次是HBG和HWC，导致HBP-HBG-HWC是MS组分的最常见簇。在此期间，代谢性不健康超重也有所增加。中国成年人的代谢健康状况一直在恶化，可能会增加非传染性疾病的负担。在过去的几十年中，MS及其组分在中国成年人中的患病率迅速增加。MS组分的高风险集群和代谢不健康的超重也随着时间的推移而增加。中国成年人代谢健康状况的动态变化，特别是血压升高和相关集群，导致非传染性疾病负担增加。
Metabolic syndrome (MS) has been increasing worldwide. The secular change in MS components, however, remains unclear. This study aimed to examine the dynamic change in metabolic health status in Chinese adults. Three population‐based surveys using multistage stratified sampling were performed in Chinese aged 35–74 years in Shanghai in 2002–2003 (n = 12,302), 2009 (n = 7,400), and 2017 (n = 19,023). MS was defined according to the Adult Treatment Panel III criteria for Asian‐Americans. Generalized Estimating Equations and Cochran‐Armitage Trend Test was used to assess the prevalence trend over the years. The prevalence of MS doubled in Chinese adults over the period (P for trend < 0.001). The largest increase occurred in younger men. Among MS components, the prevalence of high waist‐circumference (HWC), high blood glucose (HBG) and high blood pressure (HBP) increased in all subjects, whereas the prevalence of high triglycerides (HTG) and low high‐density lipoprotein cholesterol (LHC) increased in men but decreased in women. The increase in HBP contributed most to elevated MS, followed by HBG and HWC, resulting in the HBP‐HBG‐HWC the most common cluster of MS components. Metabolically unhealthy overweight also grew over the period. Metabolic health status has been exacerbating in Chinese adults and may increase burden of non‐communicable diseases. The prevalence of MS and its components increased rapidly over past decades in Chinese adults. The high‐risk clusters of MS components and metabolically unhealthy overweight also increased over time. The dynamic changes in metabolic health status in Chinese adults, particularly elevated blood pressure and related clusters, led to increasing burden of non‐communicable diseases.
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影响因子：
16.2
作者：
Isomaa, B;Almgren, P;Groop, L
通讯作者：
Groop, L
影响因子：
16.2
作者：
Li R;Lu W;Jiang QW;Li YY;Zhao GM;Shi L;Yang QD;Ruan Y;Jiang J;Zhang SN;Xu WH;Zhong WJ
通讯作者：
Zhong WJ
影响因子：
2
作者：
COLE, TJ;GREEN, PJ
通讯作者：
GREEN, PJ
影响因子：
5.8
作者：
Hamer, Mark;Bell, Joshua A.;Kivimaeki, Mika
通讯作者：
Kivimaeki, Mika
影响因子：
3.2
作者：
Cheung, Bernard M. Y.;Li, Mingfang;Lam, Karen S. L.
通讯作者：
Lam, Karen S. L.