Global NeuroAIDS roundtable.
Global NeuroAIDS roundtable.
复制标题
DOI：
10.1007/s13365-012-0143-9
复制
发表时间：
2013-02
影响因子：
3.2
通讯作者：
Wood, Charles
中科院分区：
文献类型：
--
作者：
Joseph, Jeymohan;Achim, Cristian L.;Boivin, Michael J.;Brew, Bruce J.;Clifford, David B.;Colosi, Deborah A.;Ellis, Ronald J.;Heaton, Robert K.;Gallo-Diop, Amadou;Grant, Igor;Kanmogne, Georgette D.;Kumar, Mahendra;Letendre, Scott;Marcotte, Thomas D.;Nath, Avindra;Pardo, Carlos A.;Paul, Robert H.;Pulliam, Lynn;Robertson, Kevin;Royal, Walter, III;Sacktor, Ned;Sithinamsuwan, Pasiri;Smith, Davey M.;Valcour, Victor;Wigdahl, Brian;Wood, Charles
关键词：
2012年5月，国家精神卫生研究所艾滋病研究部与第11届神经病毒学国际研讨会和2012年神经系统艾滋病毒会议一起组织了“全球神经艾滋病圆桌会议”。会议在美国纽约州纽约举行，汇集了NIMH资助的研究人员，他们目前正在非洲，亚洲，东欧和拉丁美洲从事与艾滋病神经并发症（NeuroAIDS）相关的项目，以便提供一个机会，分享他们最近的发现并讨论每个国家遇到的挑战。圆桌会议的主要目标是评估艾滋病毒相关的神经认知障碍，并确定其是否可直接归因于不同的艾滋病毒亚型或分支，并讨论全球NeuroAIDS研究的未来优先事项。在“全球神经艾滋病圆桌会议”上，对初步研究的介绍表明，与艾滋病毒有关的神经认知障碍在所有接受审查的国家都很普遍，无论该区域存在哪种艾滋病毒分支。在乌干达，HIV-1进化枝之间唯一明显的区别是与亚型A和D有关。然而，从讨论中出现的一个关键点是，有一个迫切需要标准化的神经认知评估方法在地球仪可以得出明确的结论之前，艾滋病毒的分支多样性和神经发病机制之间的关系。圆桌会议还讨论了未来的研究方向，特别强调病毒和宿主因子分子相互作用的潜力，从全球角度影响HIV相关神经认知障碍（HAND）的病理生理学。
In May 2012, the Division of AIDS Research at the National Institute of Mental Health (NIMH) organized the “Global NeuroAIDS Roundtable” in conjunction with the 11th International Symposium on Neurovirology and the 2012 Conference on HIV in the Nervous System. The meeting was held in New York, NY, USA and brought together NIMH-funded investigators who are currently working on projects related to the neurological complications of AIDS (NeuroAIDS) in Africa, Asia, Eastern Europe, and Latin America in order to provide an opportunity to share their recent findings and discuss the challenges encountered within each country. The major goals of the roundtable were to evaluate HIV-associated neurocognitive impairment and determine if it may be directly attributable to distinct HIV subtypes or clades and to discuss the future priorities for global NeuroAIDS research. At the “Global NeuroAIDS Roundtable”, presentations of preliminary research indicated that HIV-associated neurocognitive impairment is prevalent in all countries examined regardless of which HIV clade is present in the region. The only clear-cut difference between HIV-1 clades was in relation to subtypes A and D in Uganda. However, a key point that emerged from the discussions was that there is an urgent need to standardize neurocognitive assessment methodologies across the globe before definitive conclusions can be drawn regarding the relationship between HIV clade diversity and neuropathogenesis. Future research directions were also discussed at the roundtable with particular emphasis on the potential of viral and host factor molecular interactions to impact the pathophysiology of HIV-associated neurocognitive disorders (HAND) from a global perspective.
登录
查看更多内容
影响因子：
3.2
作者：
Choi, Youngjee;Townend, John;Vincent, Tim;Zaidi, Irfan;Sarge-Njie, Ramu;Jaye, Assan;Clifford, David B.
通讯作者：
Clifford, David B.
影响因子：
11.8
作者：
Sacktor, Ned;Nakasujja, Noeline;Quinn, Thomas C.
通讯作者：
Quinn, Thomas C.
影响因子：
3.2
作者：
Das Gupta, Jayashree;Satishchandra, P.;Kumar, Mahendra
通讯作者：
Kumar, Mahendra
影响因子：
3.2
作者：
Pumpradit, Wadchara;Ananworanich, Jintanat;Valcour, Victor
通讯作者：
Valcour, Victor
影响因子：
9.9
作者：
Valcour, V. G.;Sithinamsuwan, P.;Shikuma, C. M.
通讯作者：
Shikuma, C. M.