Differences in Longevity and Temperature-Driven Extrinsic Incubation Period Correlate with Varying Dengue Risk in the Arizona-Sonora Desert Region.
Differences in Longevity and Temperature-Driven Extrinsic Incubation Period Correlate with Varying Dengue Risk in the Arizona-Sonora Desert Region.
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DOI：
10.3390/v15040851
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发表时间：
2023-03-26
期刊：
影响因子：
--
通讯作者：
Riehle MA
中科院分区：
文献类型：
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作者：
Ernst KC;Walker KR;Castro-Luque AL;Schmidt C;Joy TK;Brophy M;Reyes-Castro P;Díaz-Caravantes RE;Encinas VO;Aguilera A;Gameros M;Cuevas Ruiz RE;Hayden MH;Alvarez G;Monaghan A;Williamson D;Arnbrister J;Gutiérrez EJ;Carrière Y;Riehle MA
登革热传播是由环境、埃及伊蚊、登革热病毒和人类之间一系列复杂的相互作用决定的。新地理区域的出现可能是不可预测的，一些地区几十年来已经形成了蚊子种群，但没有本地获得性传播。蚊子寿命、温度驱动的外源潜伏期 (EIP) 以及媒介与人类接触等关键因素可以强烈影响疾病传播的可能性。为了评估这些因素在登革热病毒传播地理范围边缘如何相互作用，我们在 2013 年至 2015 年夏季雨季期间在亚利桑那州-索诺拉沙漠地区的多个城市地区进行了蚊子采样。通过结合奇偶性分析和年龄相关基因 SCP-1 的相对基因表达来测量反映蚊子存活率的蚊子种群年龄结构。对现场采集的吸血蚊子进行血粉分析。使用特定地点的温度来估计 EIP，并将预测的 EIP 与蚊子年龄相结合，以估计“潜在”媒介的丰度（即年龄足以在 EIP 中生存的蚊子）。按月和年对不同城市进行比较。墨西哥索诺拉州的登革热流行城市埃莫西约和奥夫雷贡城的潜在媒介数量高于墨西哥索诺拉州非流行城市诺加莱斯。有趣的是，亚利桑那州图森市的潜在媒介估计丰度始终高于墨西哥索诺拉州登革热流行地区。血粉的物种组成没有观察到城市层面的差异。综合起来，这些数据可以深入了解蚊子活动范围生态边缘登革热传播所需的关键因素。然而，还需要进一步的研究来整合对社会和其他环境因素如何限制和加强新兴地区登革热传播的理解。
Dengue transmission is determined by a complex set of interactions between the environment, Aedes aegypti mosquitoes, dengue viruses, and humans. Emergence in new geographic areas can be unpredictable, with some regions having established mosquito populations for decades without locally acquired transmission. Key factors such as mosquito longevity, temperature-driven extrinsic incubation period (EIP), and vector–human contact can strongly influence the potential for disease transmission. To assess how these factors interact at the edge of the geographical range of dengue virus transmission, we conducted mosquito sampling in multiple urban areas located throughout the Arizona–Sonora desert region during the summer rainy seasons from 2013 to 2015. Mosquito population age structure, reflecting mosquito survivorship, was measured using a combination of parity analysis and relative gene expression of an age-related gene, SCP-1. Bloodmeal analysis was conducted on field collected blood-fed mosquitoes. Site-specific temperature was used to estimate the EIP, and this predicted EIP combined with mosquito age were combined to estimate the abundance of “potential” vectors (i.e., mosquitoes old enough to survive the EIP). Comparisons were made across cities by month and year. The dengue endemic cities Hermosillo and Ciudad Obregon, both in the state of Sonora, Mexico, had higher abundance of potential vectors than non-endemic Nogales, Sonora, Mexico. Interestingly, Tucson, Arizona consistently had a higher estimated abundance of potential vectors than dengue endemic regions of Sonora, Mexico. There were no observed city-level differences in species composition of blood meals. Combined, these data offer insights into the critical factors required for dengue transmission at the ecological edge of the mosquito’s range. However, further research is needed to integrate an understanding of how social and additional environmental factors constrain and enhance dengue transmission in emerging regions.
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影响因子：
11.8
作者：
Brunkard JM;Robles López JL;Ramirez J;Cifuentes E;Rothenberg SJ;Hunsperger EA;Moore CG;Brussolo RM;Villarreal NA;Haddad BM
通讯作者：
Haddad BM
影响因子：
3.8
作者：
Hugo LE;Jeffery JA;Trewin BJ;Wockner LF;Nguyen TY;Nguyen HL;Nghia le T;Hine E;Ryan PA;Kay BH
通讯作者：
Kay BH
影响因子：
3.7
作者：
Joy, Teresa K.;Gutierrez, Eileen H. Jeffrey;Riehle, Michael A.
通讯作者：
Riehle, Michael A.
影响因子：
--
作者：
Norman, Laura M.;Caldeira, Felipe;Callegary, James;Gray, Floyd;O' Rourke, Mary Kay;Meranza, Veronica;Van Rijn, Saskia
通讯作者：
Van Rijn, Saskia
DOI：
10.1017/s0007485300053499
发表时间：
1958-01-01
期刊：
BULL ENT RES
影响因子：
--
作者：
BAR-ZEEV, MICHA
通讯作者：
BAR-ZEEV, MICHA