Acupuncture and Reflexology for Chemotherapy-Induced Peripheral Neuropathy in Breast Cancer.
Acupuncture and Reflexology for Chemotherapy-Induced Peripheral Neuropathy in Breast Cancer.
复制标题
DOI：
10.1177/1534735417690254
复制
发表时间：
2017-09
影响因子：
2.9
通讯作者：
Geva R
中科院分区：
文献类型：
--
作者：
Ben-Horin I;Kahan P;Ryvo L;Inbar M;Lev-Ari S;Geva R
背景：化疗引起的周围神经病变 (CIPN) 影响约 30% 至 40% 接受神经病变药物治疗的患者，治疗主要是对症治疗。目前可用的干预措施收效甚微。研究设计：本研究旨在回顾性分析针灸和反射疗法缓解乳腺癌患者 CIPN 的功效。方法：回顾了 2011 年至 2012 年间根据我们的神经病针灸和反射疗法 (ART-N) 方案接受化疗和 CIPN 治疗的连续 30 名乳腺癌患者的病历。在基线、治疗期间和治疗后评估症状严重程度。结果：检索到30例因CIPN而接受化疗和ART-N联合治疗的乳腺癌患者的记录。两项记录不完整，总共有 28 名患者参与了该研究。 20 名患者（71%）患有感觉神经病，7 名患者（25%）患有运动神经病，1 名患者（4%）同时患有感觉神经病和运动神经病。自开始 ART-N 方案后 12 个月时，20 名 1 至 2 级神经病变患者中只有 2 名 (10%) 仍报告症状。所有 8 名出现 3 至 4 级神经病变的患者在 12 个月的评估中均无症状。总体而言，26 名患者 (93%) 的 CIPN 症状完全消失。结论：这项研究的结果表明，针灸和反射疗法的联合方案有可能改善乳腺癌患者的 CIPN 症状。该方案应在包含对照组的更大队列中进行验证。它还需要进行测试作为预防性干预措施。
Background: Treatment of chemotherapy-induced peripheral neuropathy (CIPN), which affects approximately 30% to 40% of patients treated with neuropathy-causing agents, is mainly symptomatic. Currently available interventions are of little benefit. Study Design: This study was conducted as a retrospective analysis of the efficacy of acupuncture and reflexology in alleviating CIPN in breast cancer patients. Methods: Medical records of 30 consecutive breast cancer patients who received both chemotherapy and treatment for CIPN according to our Acupuncture and Reflexology Treatment for Neuropathy (ART-N) protocol between 2011 and 2012 were reviewed. Symptom severity was rated at baseline, during, and after treatment. Results: The records of 30 breast cancer patients who had been concomitantly treated with chemotherapy and ART-N for CIPN were retrieved. Two records were incomplete, leaving a total of 28 patients who were enrolled into the study. Twenty patients (71%) had sensory neuropathy, 7 (25%) had motor neuropathy, and 1 (4%) had both sensory and motor neuropathy. Only 2 (10%) of the 20 patients with grades 1 to 2 neuropathy still reported symptoms at 12 months since starting the ART-N protocol. All 8 patients who presented with grades 3 to 4 neuropathy were symptom-free at the 12-month evaluation. Overall, 26 patients (93%) had complete resolution of CIPN symptoms. Conclusion: The results of this study demonstrated that a joint protocol of acupuncture and reflexology has a potential to improve symptoms of CIPN in breast cancer patients. The protocol should be validated on a larger cohort with a control group. It also warrants testing as a preventive intervention.
登录
查看更多内容
影响因子：
2.5
作者：
Schroeder, Sven;Meyer-Hamme, Gesa;Epplee, Susanne
通讯作者：
Epplee, Susanne
影响因子：
50.5
作者：
Molassiotis, A;Fernandez-Ortega, P;Patiraki, E
通讯作者：
Patiraki, E
影响因子：
9.9
作者：
Chaudhry, V;Chaudhry, M;Griffin, JW
通讯作者：
Griffin, JW
影响因子：
2.4
作者：
Kuroi, Katsumasa;Shimozuma, Kojiro;Hausheer, Frederick H.
通讯作者：
Hausheer, Frederick H.
影响因子：
3.1
作者：
Cunningham, Joan Elizabeth;Kelechi, Teresa;Chin, Steve H.
通讯作者：
Chin, Steve H.