Factors Involved in Morphogenesis in the Muscle-Tendon-Bone Complex.
Factors Involved in Morphogenesis in the Muscle-Tendon-Bone Complex.
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DOI：
10.3390/ijms22126365
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发表时间：
2021-06-14
影响因子：
5.6
通讯作者：
Yamamoto M
中科院分区：
文献类型：
--
作者：
Abe S;Yamamoto M
身体运动功能的下降与口腔和喉咙的肌肉质量和功能下降有关;然而，肌肉和骨骼连接处的老化也被认为是一个相关因素。已经发表了关于肌肉、肌腱和骨骼的基础和临床研究，每一项研究都是独立考虑的。然而，近年来，研究从各种角度关注作为肌肉-肌腱-骨复合体的肌肉附着，并且关于SRY-box 9（Sox 9）和Mohawk（Mkx）的知识越来越多，这已被确定为共同的控制因素和关键因素。肌生长抑制素是一种抑制肌肉生长的因子，已被确定为肌肉-肌腱-骨复合体终身结构维持机制中的潜在关键因素。最近的研究结果也揭示了当今超级老龄社会中运动器官复合体形态稳定机制的各个方面，并将为预防老年人运动功能下降的治疗奠定基础。
A decline in the body’s motor functions has been linked to decreased muscle mass and function in the oral cavity and throat; however, aging of the junctions of the muscles and bones has also been identified as an associated factor. Basic and clinical studies on the muscles, tendons and bones, each considered independently, have been published. In recent years, however, research has focused on muscle attachment as the muscle–tendon–bone complex from various perspectives, and there is a growing body of knowledge on SRY-box9 (Sox9) and Mohawk(Mkx), which has been identified as a common controlling factor and a key element. Myostatin, a factor that inhibits muscle growth, has been identified as a potential key element in the mechanisms of lifetime structural maintenance of the muscle–tendon–bone complex. Findings in recent studies have also uncovered aspects of the mechanisms of motor organ complex morphostasis in the superaged society of today and will lay the groundwork for treatments to prevent motor function decline in older adults.
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影响因子：
2.5
作者：
Anderson, DM;Arredondo, J;Rawls, A
通讯作者：
Rawls, A
影响因子：
3.7
作者：
Ideo K;Tokunaga T;Shukunami C;Takimoto A;Yoshimoto Y;Yonemitsu R;Karasugi T;Mizuta H;Hiraki Y;Miyamoto T
通讯作者：
Miyamoto T
DOI：
10.1016/j.biocel.2009.10.003
发表时间：
2010-01-01
影响因子：
4
作者：
Furumatsu, Takayuki;Shukunami, Chisa;Ozaki, Toshifumi
通讯作者：
Ozaki, Toshifumi
影响因子：
2.7
作者：
Honda, Hidemitsu;Abe, Shinichi;Ide, Yoshinobu
通讯作者：
Ide, Yoshinobu
影响因子：
0.9
作者：
Kocamis, H;Gulmez, N;Nazli, M
通讯作者：
Nazli, M