Well-differentiated extraskeletal osteosarcoma arising from the retroperitoneum that recurred as anaplastic spindle cell sarcoma.
Well-differentiated extraskeletal osteosarcoma arising from the retroperitoneum that recurred as anaplastic spindle cell sarcoma.
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DOI：
10.1155/2010/327591
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发表时间：
2010
影响因子：
0.8
通讯作者：
Masuda M
中科院分区：
文献类型：
--
作者：
Arai H;Rino Y;Nishii T;Yukawa N;Wada N;Oshiro H;Ishida T;Nakaigawa N;Masuda M
骨外骨肉瘤是一种罕见的高度恶性软组织肉瘤。高分化的骨肉瘤被认为比经典的骨肉瘤有更好的预后，但也有复发后去分化的报道。我们报告一位62岁日本女性原发性腹膜后骨肉瘤的病例。腹部电脑断层显示一个大的肿块，并在右侧腹膜后间隙弥漫性钙化，并进行肿瘤切除术。组织病理学诊断为腹膜后高分化骨肉瘤。每6个月进行一次CT随访，无辅助放疗和化疗，随访31个月，直至腹膜后间变性高级别梭形细胞肉瘤复发。我们的病例是第七次报道的分化良好的皮肤外肉瘤，也是第一次出现在腹膜后并作为完全去分化的梭形细胞肉瘤复发。
Extraskeletal osteosarcoma is an uncommon high-grade malignant soft tissue sarcoma. Well-differentiated extraskeletal osteosarcoma is thought to have a better prognosis than classical extraskeletal osteosarcoma, but dedifferentiation after recurrence has also been reported. We present a case of a primary retroperitoneal extraskeletal osteosarcoma in a 62-year-old Japanese woman. Abdominal CT revealed a large mass with diffuse calcification in the right retroperitoneal space and tumor resection was performed. The histopathological diagnosis was well-differentiated retroperitoneal extraskeletal osteosarcoma. She was followed up by CT every 6 months without adjuvant radiotherapy and chemotherapy for 31 months until anaplastic high-grade spindle cell sarcoma recurred in the retroperitoneum. Our case is the seventh reported description of well-differentiated extraskeletal sarcoma, and the first to arise in the retroperitoneum and recur as an entirely dedifferentiated spindle cell sarcoma.
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影响因子：
2.1
作者：
Okada, K;Ito, H;Itoi, E
通讯作者：
Itoi, E
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JAFFE, HL
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Steiner, GC