Efficient method for volumetric assessment of peak blood flow velocity using 4D flow MRI.
Efficient method for volumetric assessment of peak blood flow velocity using 4D flow MRI.
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DOI：
10.1002/jmri.25305
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发表时间：
2016-12
影响因子：
4.4
通讯作者：
Schnell, Susanne
中科院分区：
文献类型：
--
作者：
Rose, Michael J.;Jarvis, Kelly;Chowdhary, Varun;Barker, Alex J.;Allen, Bradley D.;Robinson, Joshua D.;Markl, Michael;Rigsby, Cynthia K.;Schnell, Susanne
旨在测试基于4D血流MRI速度数据使用最大强度图（MIP）评估二尖瓣主动脉瓣（BAV）患者队列收缩期峰值速度的可行性和有效性。对51例BAV患者进行了1.5 T的4D flow MRI。MIP由4D Flow MRI速度数据生成，并由2名用户用于确定3个感兴趣区域（ROI）的峰值速度：升主动脉（AAo）、主动脉弓和降主动脉。在36例患者的子队列中，将Ao的4D血流MRI峰值速度与2D相位对比MRI（2D PCMRI）记录的峰值速度进行比较，并在34例患者的子队列中与多普勒超声心动图记录的峰值速度进行比较。比较了每个观察者记录的所有ROI的4D血流MRI峰值速度，以测试观察者间的变异性。与2D PCMRI相比，4D flow MRI记录的速度显著更高（2.04 ± 0.71 m/s vs 1.69 ± 0.79 m/s，17.2%差异，p < 0.001），与多普勒超声心动图相比，速度相似。观察者之间的平均差异为0.005 m/s，组内相关系数为0.98，具有良好的一致性。4D Flow MRI速度MIP允许有效测量BAV患者的峰值速度，其准确度高于2D PCMRI，与多普勒超声心动图相似。
To test the feasibility and effectiveness of using maximum intensity plots (MIPs) based on 4D flow MRI velocity data to assess systolic peak velocities in a cohort of bicuspid aortic valve (BAV) patients. 4D flow MRI at 1.5 T was performed on 51 BAV patients. MIPs were generated from the 4D flow MRI velocity data and used by 2 users to determine peak velocities in 3 regions of interest (ROI): ascending aorta (AAo), aortic arch and descending aorta. 4D flow MRI peak velocities in the AAo were compared to peak velocities recorded by 2D phase contrast MRI (2D PCMRI) in a subcohort of 36 patients and by Doppler echocardiography in a subcohort of 34 patients. 4D flow MRI peak velocities recorded by each observer were compared for all ROIs to test for inter-observer variability. 4D flow MRI recorded significantly higher velocities compared to 2D PCMRI (2.04 ± 0.71 m/s vs 1.69 ± 0.79 m/s, 17.2% difference, p < 0.001) and similar velocities compared to Doppler echocardiography. There was excellent agreement between the observers with a mean difference of 0.005 m/s and an intraclass correlation coefficient of 0.98. 4D flow MRI velocity MIPs allow for efficient measurement of peak velocities in BAV patients with higher accuracy than 2D PCMRI and similar accuracy to Doppler echocardiography.
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影响因子：
4.4
作者：
Markl, Michael;Harloff, Andreas;Frydrychowicz, Alex
通讯作者：
Frydrychowicz, Alex
影响因子：
4.8
作者：
SONDERGAARD, L;HILDEBRANDT, P;HENRIKSEN, O
通讯作者：
HENRIKSEN, O
影响因子：
2.9
作者：
GILL, RW
通讯作者：
GILL, RW
影响因子：
3.3
作者：
Huang, F;Akao, J;Limkeman, M
通讯作者：
Limkeman, M
影响因子：
2.3
作者：
Gabbour, Maya;Schnell, Susanne;Jarvis, Kelly;Robinson, Joshua D.;Markl, Michael;Rigsby, Cynthia K.
通讯作者：
Rigsby, Cynthia K.