Cannabis use and stressful life events during the perinatal period: cross-sectional results from Pregnancy Risk Assessment Monitoring System (PRAMS) data, 2016.
Cannabis use and stressful life events during the perinatal period: cross-sectional results from Pregnancy Risk Assessment Monitoring System (PRAMS) data, 2016.
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DOI：
10.1111/add.15003
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发表时间：
2020-09
期刊：
影响因子：
6
通讯作者：
al'Absi, Mustafa
中科院分区：
文献类型：
--
作者：
Allen, Alicia M.;Jung, Alesia M.;Alexander, Adam C.;Allen, Sharon S.;Ward, Kenneth D.;al'Absi, Mustafa
我们的目的是确定分娩前一年的压力性生活事件（SLEs）与（1）孕前大麻使用，（2）怀孕期间停止使用大麻和（3）产后复发大麻使用之间的关联。我们使用了来自妊娠风险评估监测系统（PRAMS）2016的数据，这是一个基于人群的横断面监测系统。在美国的五个州--阿拉斯加、科罗拉多、缅因州、密歇根州和华盛顿州进行了邮寄和电话调查。在过去6个月内分娩活婴并有大麻使用数据的妇女（n = 6061）。自我报告的数据包括SLE（分娩前12个月内14起个体事件的回答是/否）和大麻使用[妊娠前、妊娠期间和调查时（产后约2-6个月）是/否]。SLE与大麻使用（主要结局）之间的关联在logistic回归模型中进行了检查，该模型针对孕产妇人口统计学（例如年龄，种族，教育），地理（即居住州）和吸烟进行了调整。在怀孕前，16.4%（997/6061）的受访者赞成使用大麻，36.4%（363/997）在怀孕期间继续使用大麻。在63.6%（634/997）未报告在怀孕期间使用大麻的人中，23.2%（147/634）在产后期间重新使用大麻。14例可能的SLE中有9例与孕前使用大麻的几率增加有关[例如，丈夫/伴侣或母亲入狱，调整后的比值比（aOR）= 2.16，95%置信区间（CI）= 1.30-3.62]，4例与妊娠期间继续使用大麻的几率增加有关（例如，丈夫/伴侣失业，aOR = 2.19，95%CI = 1.21-3.96）。产后大麻复发的几率与两种SLE显著相关（丈夫/伴侣说他们不想怀孕，aOR = 2.86，CI = 1.10-7.72;丈夫/伴侣或母亲入狱，aOR = 0.37，95%CI = 0.13-1.00）。分娩前一年的压力生活事件似乎与妇女在围产期使用大麻的可能性更大有关，特别是在怀孕前。
We aimed to determine the association between stressful life events (SLEs) in the year prior to childbirth with (1) pre-pregnancy cannabis use, (2) cessation of cannabis use during pregnancy and (3) postpartum relapse to cannabis use. We used data from the Pregnancy Risk Assessment Monitoring System (PRAMS) 2016, a cross-sectional, population-based surveillance system. Mailed and telephone surveys conducted in five states—Alaska, Colorado, Maine, Michigan and Washington—in the United States. Women (n = 6061) who delivered a live infant within the last 6 months and had data on cannabis use. Self-reported data included SLEs (yes/no response for 14 individual events in the 12 months prior to childbirth) and cannabis use [yes/no prior to pregnancy, during pregnancy, and at the time of the survey (approximately 2–6 months postpartum)]. The associations between SLEs and cannabis use (primary outcomes) were examined in logistic regression models adjusted for maternal demographics (e.g. age, race, education), geography (i.e. state of residence) and cigarette smoking. Pre-pregnancy, 16.4% (997/6061) of respondents endorsed using cannabis, with 36.4% (363/997) continuing cannabis use during pregnancy. Among the 63.6% (634/997) who did not report use during pregnancy, 23.2% (147/634) relapsed to cannabis use during the postpartum. Nine of the 14 possible SLEs were associated with increased odds of pre-pregnancy cannabis use [e.g. husband/partner or mother went to jail, adjusted odds ratio (aOR) = 2.16, 95% confidence interval (CI) = 1.30–3.62] and four were associated with increased odds of continued cannabis use during pregnancy (e.g. husband/partner lost job, aOR = 2.19, 95% CI = 1.21–3.96). The odds of postpartum relapse to cannabis were significantly associated with two SLEs (husband/partner said they did not want pregnancy, aOR = 2.86, CI = 1.10–7.72; husband/partner or mother went to jail, aOR = 0.37, 95% CI = 0.13–1.00). Stressful life events during the year prior to childbirth appear to be linked to greater odds of women’s cannabis use during the perinatal period, especially during pre-pregnancy.
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